Results 41 to 50 of about 248,303 (301)

Sequencing genes in silico using single nucleotide polymorphisms

BMC Genetics, 2012
Background The advent of high throughput sequencing technology has enabled the 1000 Genomes Project Pilot 3 to generate complete sequence data for more than 906 genes and 8,140 exons representing 697 subjects.
Zhang Xinyi, Zhang Bo, Li Shuying, Huang Xin, Hansen John A, Zhao Lue   +5 more
doaj   +1 more source

PhosR enables processing and functional analysis of phosphoproteomic data

Cell Reports, 2021
Summary: Mass spectrometry (MS)-based phosphoproteomics has revolutionized our ability to profile phosphorylation-based signaling in cells and tissues on a global scale.
Hani Jieun Kim, Taiyun Kim, Nolan J. Hoffman, Di Xiao, David E. James, Sean J. Humphrey, Pengyi Yang   +6 more
doaj   +1 more source

The Challenges of Chromosome Y Analysis and the Implications for Chronic Kidney Disease

Frontiers in Genetics, 2019
The role of chromosome Y in chronic kidney disease (CKD) remains unknown, as chromosome Y is typically excluded from genetic analysis in CKD. The complex, sex-specific presentation of CKD could be influenced by chromosome Y genetic variation, but there ...
Kerry Anderson, Marisa Cañadas-Garre, Robyn Chambers, Alexander Peter Maxwell, Alexander Peter Maxwell, Amy Jayne McKnight   +5 more
doaj   +1 more source

Decoding the diversity of killer immunoglobulin-like receptors by deep sequencing and a high-resolution imputation method

Cell Genomics, 2022
Summary: The killer cell immunoglobulin-like receptor (KIR) recognizes human leukocyte antigen (HLA) class I molecules and modulates the function of natural killer cells.
Saori Sakaue, Kazuyoshi Hosomichi, Jun Hirata, Hirofumi Nakaoka, Keiko Yamazaki, Makoto Yawata, Nobuyo Yawata, Tatsuhiko Naito, Junji Umeno, Takaaki Kawaguchi, Toshiyuki Matsui, Satoshi Motoya, Yasuo Suzuki, Hidetoshi Inoko, Atsushi Tajima, Takayuki Morisaki, Koichi Matsuda, Yoichiro Kamatani, Kazuhiko Yamamoto, Ituro Inoue, Yukinori Okada   +20 more
doaj   +1 more source

Multiple imputation of missing covariates with non-linear effects and interactions: an evaluation of statistical methods. [PDF]

, 2012
BACKGROUND: Multiple imputation is often used for missing data. When a model contains as covariates more than one function of a variable, it is not obvious how best to impute missing values in these covariates.
Bartlett Jonathan W, Bartlett, Jonathan W, White, Ian R, Seaman Shaun R, White Ian R, Ian R White, Seaman, Shaun R, Shaun R Seaman, Jonathan W Bartlett   +8 more
core   +2 more sources

Learning-Based Adaptive Imputation Methodwith kNN Algorithm for Missing Power Data

Energies, 2017
This paper proposes a learning-based adaptive imputation method (LAI) for imputing missing power data in an energy system. This method estimates the missing power data by using the pattern that appears in the collected data. Here, in order to capture the
Minkyung Kim, Sangdon Park, Joohyung Lee, Yongjae Joo, Jun Kyun Choi   +4 more
doaj   +1 more source

Data‐Driven Estimation of Groundwater Level Time‐Series at Unmonitored Sites Using Comparative Regional Analysis

Water Resources Research, 2023
A new method is presented to efficiently estimate daily groundwater level time series at unmonitored sites by linking groundwater dynamics to local hydrogeological system controls.
E. Haaf, M. Giese, T. Reimann, R. Barthel   +3 more
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

THE IMPUTABLE DEED / THE IMPUTABLE ACTION

Agora International Journal of Juridical Sciences, 2013
The criminal standards, meant to the protection of the social values, establish theobjectives and subjective conditions that must be fulfilled as a behavior to be illicit.Therefore, finding the illicit/the unlawful character of the behavior does not means that thiscan be already considered infringement of law, for the existence of the offense needful ...
openaire   +2 more sources