Impact of field number and monitor units per segment on magnetic resonance-guided hypofractionated stereotactic radiotherapy for brain metastases: plan quality, deliverability, and robustness trade-offs. [PDF]
Ren S +10 more
europepmc +1 more source
ABSTRACT Background Nuclear protein in testis (NUT) carcinoma is a rare, aggressive malignancy driven by NUTM1 rearrangement, often misdiagnosed as squamous cell carcinoma, with no established standard therapy. This report describes the clinical course and treatment resistance in primary laryngeal NUT carcinoma and provides insights into potential ...
Masafumi Kanno +15 more
wiley +1 more source
Dosimetric Evaluation of MR-Guided IMRT and VMAT Techniques for Early-Stage Glottic Cancer: A Pilot Comparative Planning Study. [PDF]
Rudžianskas V +4 more
europepmc +1 more source
Non‐Metastatic Squamous Cell Carcinoma of the Oropharynx: Primary Surgery or (Chemo)radiotherapy?
ABSTRACT Background In patients with locally advanced, non‐metastatic oropharyngeal squamous cell carcinoma (OPSCC), surgery‐based and nonsurgical treatment approaches have not been adequately compared in randomized Phase III clinical trials. Current clinical guidelines recommend various surgical and nonsurgical strategies across disease stages for ...
Primož Strojan +12 more
wiley +1 more source
The Evolution of Radiation Therapy in Children's Oncology Group Trials, From 1998 to 2025. [PDF]
Gallitto M +13 more
europepmc +1 more source
Molecular Functions and Drug Prediction of MMP1 and TGFBR2 in Nasopharyngeal Carcinoma
MMP1 and TGFBR2 were validated by machine learning and external datasets as the candidate genes. Dexamethasone showed strong binding affinity to MMP1 (−7.72 kcal/mol) and TGFBR2 (−7.27 kcal/mol) in docking studies. Knockdown of MMP1 repressed the malignant phenotypes of NPC cells.
Feng Wang +5 more
wiley +1 more source
Identifying risk factors for osteoradionecrosis of the jaws: a systematic review and meta-analysis. [PDF]
de Carli RLB +4 more
europepmc +1 more source
A 22% breath‐hold failure and exclusion rate highlighted major communication barriers for CALD breast radiotherapy patients. In response, a multilingual app was developed to deliver translated coaching for DIBH and EBH in seven languages, improving health equity within the local health district through early education, patient‐friendly FAQs, and ...
Toby Lowe +8 more
wiley +1 more source
Definitive Chemoradiotherapy Versus Total Laryngectomy Followed by Postoperative Therapy in Selected T3-T4a N0-N1 Laryngeal Cancer: Comparative Outcomes. [PDF]
Ozkaya Akagunduz O +10 more
europepmc +1 more source
Radiotherapy‐Induced Otitis Media With Effusion in Nasopharyngeal Carcinoma: A Meta‐Analysis
This meta‐analysis of eight studies comprising 582 NPC patients provides the first quantitative synthesis of radiotherapy‐induced otitis media with effusion (OME), demonstrating a significant overall risk difference of 0.18 (95% CI: −0.06 to 0.42, p < 0.0001) in OME naive ears.
Nevin Yi Meng Chua +3 more
wiley +1 more source

