Results 191 to 200 of about 44,626 (291)

Laryngeal NUT Carcinoma With BRD4::NUTM1 Fusion: A 4‐Year Clinical Course Highlighting the Limitations of Current Multimodal Therapy

open access: yesCancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Nuclear protein in testis (NUT) carcinoma is a rare, aggressive malignancy driven by NUTM1 rearrangement, often misdiagnosed as squamous cell carcinoma, with no established standard therapy. This report describes the clinical course and treatment resistance in primary laryngeal NUT carcinoma and provides insights into potential ...
Masafumi Kanno   +15 more
wiley   +1 more source

Dosimetric Evaluation of MR-Guided IMRT and VMAT Techniques for Early-Stage Glottic Cancer: A Pilot Comparative Planning Study. [PDF]

open access: yesMedicina (Kaunas)
Rudžianskas V   +4 more
europepmc   +1 more source

Non‐Metastatic Squamous Cell Carcinoma of the Oropharynx: Primary Surgery or (Chemo)radiotherapy?

open access: yesHead &Neck, Volume 48, Issue 9, Page 2541-2556, September 2026.
ABSTRACT Background In patients with locally advanced, non‐metastatic oropharyngeal squamous cell carcinoma (OPSCC), surgery‐based and nonsurgical treatment approaches have not been adequately compared in randomized Phase III clinical trials. Current clinical guidelines recommend various surgical and nonsurgical strategies across disease stages for ...
Primož Strojan   +12 more
wiley   +1 more source

The Evolution of Radiation Therapy in Children's Oncology Group Trials, From 1998 to 2025. [PDF]

open access: yesInt J Radiat Oncol Biol Phys
Gallitto M   +13 more
europepmc   +1 more source

Molecular Functions and Drug Prediction of MMP1 and TGFBR2 in Nasopharyngeal Carcinoma

open access: yesJournal of Clinical Laboratory Analysis, Volume 40, Issue 18, September 2026.
MMP1 and TGFBR2 were validated by machine learning and external datasets as the candidate genes. Dexamethasone showed strong binding affinity to MMP1 (−7.72 kcal/mol) and TGFBR2 (−7.27 kcal/mol) in docking studies. Knockdown of MMP1 repressed the malignant phenotypes of NPC cells.
Feng Wang   +5 more
wiley   +1 more source

Identifying risk factors for osteoradionecrosis of the jaws: a systematic review and meta-analysis. [PDF]

open access: yesClin Oral Investig
de Carli RLB   +4 more
europepmc   +1 more source

Improving Equity of Care for Culturally and Linguistically Diverse Patients: Utilising Multilingual Software to Support Breath‐Hold Breast Radiation Therapy

open access: yesJournal of Medical Radiation Sciences, Volume 73, Issue 3, Page 352-358, September 2026.
A 22% breath‐hold failure and exclusion rate highlighted major communication barriers for CALD breast radiotherapy patients. In response, a multilingual app was developed to deliver translated coaching for DIBH and EBH in seven languages, improving health equity within the local health district through early education, patient‐friendly FAQs, and ...
Toby Lowe   +8 more
wiley   +1 more source

Definitive Chemoradiotherapy Versus Total Laryngectomy Followed by Postoperative Therapy in Selected T3-T4a N0-N1 Laryngeal Cancer: Comparative Outcomes. [PDF]

open access: yesCancers (Basel)
Ozkaya Akagunduz O   +10 more
europepmc   +1 more source

Radiotherapy‐Induced Otitis Media With Effusion in Nasopharyngeal Carcinoma: A Meta‐Analysis

open access: yesThe Laryngoscope, Volume 136, Issue 9, Page 3718-3731, September 2026.
This meta‐analysis of eight studies comprising 582 NPC patients provides the first quantitative synthesis of radiotherapy‐induced otitis media with effusion (OME), demonstrating a significant overall risk difference of 0.18 (95% CI: −0.06 to 0.42, p < 0.0001) in OME naive ears.
Nevin Yi Meng Chua   +3 more
wiley   +1 more source

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