Results 211 to 220 of about 44,626 (291)

Long‐Term Prognosis and Immunotranscriptomic Landscape in Esophageal Squamous Cell Carcinoma With Different Pathological Responses to Neoadjuvant Chemoradiotherapy: A Retrospective Cohort Study

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This study comprehensively characterizes the long‐term prognosis and immunotranscriptomic landscape associated with different tumor regression grades (TRGs) in esophageal squamous cell carcinoma (ESCC) following neoadjuvant chemoradiotherapy. By integrating bulk RNA‐seq, single‐cell transcriptomics, and multiplexed immunohistochemistry, we demonstrate ...
Jianye Yuan, Zelin Weng, Xinke Zhang, Fangqi Deng, Zihui Tan, Jian Zhong, Rui Chen, Xiuying Xie, Xiaodan Lin, Ting Lin, Yan Huang, Qianwen Liu, Jing Wen, Jianhua Fu   +13 more
wiley   +1 more source

Variable-interval temporal feathering to optimize organs-at-risk repair for head and neck adaptive radiotherapy. [PDF]

Phys Imaging Radiat Oncol
Karagoz A, Hemmati M, Nosrat F, Mavroidis P, Dede C, McCullum LB, Garcia R, Hosseinian S, Scott JG, Bates JE, Enderling H, Mohamed ASR, Brock KK, Schaefer AJ, Fuller CD.   +14 more
europepmc   +1 more source

Multi‐modal direct LINAC parameter prediction for pancreatic VMAT: An optimization‐free approach

Medical Physics, Volume 53, Issue 9, September 2026.
Abstract Background Pancreatic cancer Volumetric Modulated Arc Therapy (VMAT) planning presents a significant dosimetric challenge due to the high‐dose gradients required to spare adjacent, radiosensitive organs at risk (OARs) like the stomach and duodenum. This anatomical complexity has limited the scope of automated planning for this site.
Zixu Guan, Yukine Shimizu, Takahiro Iwai, Michio Yoshimura, Takashi Mizowaki, Mitsuhiro Nakamura   +5 more
wiley   +1 more source

Four-dimensional computed tomography ventilation imaging-guided radiotherapy planning in different techniques for lung cancer. [PDF]

Front Oncol
Yang SQ, Yu H, Yang YL, Wang C, Li Y, Guo DF, Lin CS, Li C, Cai ZQ.   +8 more
europepmc   +1 more source

Roadmap for the implementation of particle minibeam therapy

Medical Physics, Volume 53, Issue 9, September 2026.
Abstract Particle minibeam therapy (PMBT) has emerged as an advanced modality within spatially fractionated radiation therapy, using the physical properties of protons, ions, and electrons to achieve superior normal tissue sparing whilst preserving spatial dose distribution at depths that are unachievable in conventional kV or MV X‐rays.
Reem Ahmad, Oxana Actis, Adam H. Aitkenhead, Richard A. Amos, Niels Bassler, Catherine Burne, Pankaj Chaudhary, Gerd Datzmann, Umberto Deut, Fabio Di Martino, Rebecca Habgood, Simon Jolly, Emmanuel Jouglar, Eva Kasanda, Nigel Lee, Dominic Leiser, Xiangkun Li, Giuliana Milluzzo, Jessica Neubauer, Kelvin Ng Wei Siang, Hugo Palmans, Yolanda Prezado, Judith Reindl, Francesco Romano, Loris Roncali, Aikaterini Rousseti, Thomas E. Schmid, Ileana Silvestre Patallo, Frank Stephan, Anna Subiel, Edward Taylor, Annalisa Walpen, Samuel Flynn   +32 more
wiley   +1 more source

External Beam Breast and Chest Wall Re-Irradiation Following Resection of Ipsilateral Breast Cancer Recurrence: Dose-Toxicity Relationships and Long-Term Oncologic Outcomes. [PDF]

Cancers (Basel)
Ghosh S, Soliman H, Chow E, Chen H, Leung E, Karam I, Rakovitch E, Safavi AH, Vesprini D, Czarnota GJ.   +9 more
europepmc   +1 more source

Radiotherapy and Immunotherapy In Hepatocellular Carcinoma: Priming the Tumor Immune Microenvironment From Bench To Bedside

Precision Radiation Oncology, Volume 10, Issue 3, Page 417-427, September 2026.
The dual immunomodulatory network of radiotherapy in hepatocellular carcinoma. Radiotherapy initiates its effects by inducing immunogenic cell death and DNA double‐strand breaks. Immune Activation: Cytosolic DNA from damaged cells activates the cGAS‐STING pathway, triggering IRF3/NF‐κB‐mediated type I interferon production. This enhances dendritic cell
Zhigang Fu, Yang Zhang, Zuomin Wang, Zongjuan Li, Shisuo Du   +4 more
wiley   +1 more source

Initial experience of clinical implementation of an Online Simulation-free CBCT-based Adaptive Radiotherapy (OSCAR) workflow for palliative and urgent treatment indications. [PDF]

J Appl Clin Med Phys
Schindhelm R, Richter A, Kleine P, Tamihardja J, Lewitzki V, Polat B, Zimmermann M, Mantel F, Fischer T, Heß S, Lawrenz I, Künzig F, Schilling F, Wittig-Sauerwein A, Razinskas G.   +14 more
europepmc   +1 more source

Safety, efficacy, pharmacokinetics, and mechanisms of novel 10B‐boronophenylalanine combined with a radio‐frequency quadrupole accelerator in boron neutron capture therapy: A preclinical study in head and neck squamous cell carcinoma

Precision Radiation Oncology, Volume 10, Issue 3, Page 333-346, September 2026.
This study demonstrates that the novel 10B‐BPA‐based BNCT system, combined with an RFQ accelerator, effectively targets head and neck squamous cell carcinoma. It induces tumor regression safely and efficiently by triggering DNA damage and activating the ROS/HIF‐1α/NF‐κB pathway, leading to caspase‐3‐mediated apoptosis.
Zhaoyuan Zhang, Junyan Li, Minhua Fan, Huafu Ouyang, Qiubo Chu, Huijie Yan, Yannan Zheng, Linxuan Huang, Gui Bao, Zhenting Ma, Shaobo Huang, Lin Li, Xiao Xu, Zhigang Liu   +13 more
wiley   +1 more source

Navigating the Role of Radiotherapy for Extremity Soft Tissue Sarcomas. [PDF]

Biomedicines
Nyqvist E, Linder-Stragliotto C, Lofgren J, Tsagkozis P.   +3 more
europepmc   +1 more source