Results 41 to 50 of about 74,991 (297)

Continuous photon energy modulation in IMRT of pancreatic cancer

Frontiers in Physics, 2023
Purpose: To develop a novel IMRT optimization method based on the principle of photon energy synthesis that simultaneously optimizes fluence map and beamlet energy.
Xile Zhang, Xile Zhang, Fugen Zhou, Fugen Zhou, Bo Liu, Bo Liu, Tianyu Xiong, Xiangzhi Bai, Xiangzhi Bai, Qiuwen Wu   +9 more
doaj   +1 more source

Clinical benefit of adding oxaliplatin to standard neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a meta-analysis : Oxaliplatin in neoadjuvant treatment for rectal cancer [PDF]

, 2017
. Background: To evaluate the treatment tolerance and clinical outcomes in patients aged 70 years and older with locally advanced oropharyngeal cancer treated by definitive intensity-modulated radiation therapy (IMRT).
Benevento, Ilaria, Bulzonetti, Nadia, Caiazzo, Rossella, DE FELICE, Francesca, Magnante, ANNA LISA, Musio, Daniela, Tombolini, Vincenzo   +6 more
core   +1 more source

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

Advanced Science, EarlyView.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu, Yujia Zhou, Zihan Zhang, Rong Ma, Luyi Ruan, Liqing Miao, Boxin Zhang, Huihui Ji, Tianfeng Chen, Xueqiong Zhu   +9 more
wiley   +1 more source

After Effects of Radiation on the Caries Status of Head and Neck Cancer Patients − A Six-Month Clinical Trial

Journal of Pharmacy and Bioallied Sciences
Background: Head and neck cancer patients undergoing radiation therapy (RT) are at an increased risk of dental caries due to radiation-induced damage to salivary glands.
Upasana Reddy, Mithra N. Hegde, Aditya Shetty, Mallikarjuna Rao Koduru, Neevan Dsouza   +4 more
doaj   +1 more source

Postoperative and Functional Outcomes of Oropharyngectomy in Irradiated Neck for Recurrent or Metachronous Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Objective To evaluate predictors of postoperative and functional outcomes following salvage oropharyngectomy. Methods In this single‐center retrospective study, we included all patients who underwent an oropharyngectomy in an irradiated neck for recurrent or metachronous cancer between 2014 and 2023. Results We included 94 patients.
Jade Saykaly, Agnès Dupret‐Bories, Sébastien Vergez, Virginie Woisard, Benjamin Vairel, Jérôme Sarini, Ana Cavillon, Emilien Chabrillac   +7 more
wiley   +1 more source

Different Pattern of Treatment Failure After Chemoradiation Between p16+ and p16− Patients Affected by Oropharyngeal Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Oropharyngeal cancer (OPC) exhibits distinct clinical behaviors according to HPV/p16 status and smoking exposure. While HPV‐positive OPC generally shows superior survival, differences in recurrence patterns remain unclear. Methods A retrospective multicenter analysis of 674 AJCC VII edition Stage III–IVa/b OPC patients treated with ...
Riccardo Gili, Paolo Bossi, Luca Lalli, Lisa Francesca Linda Licitra, Marta Maddalo, Almalina Bacigalupo, Liliana Belgioia, Jon Cacicedo, Nadia Facchinetti, Almudena Garcia Castano, Marc Oliva, Pierluigi Bonomo, Giuseppe Sanguineti, Pierfrancesco Franco, Athanassios Argiris, Amanda Psyrri, Ester Orlandi   +16 more
wiley   +1 more source

Incidence and Site‐Specific Risk Factors of Jaw Osteoradionecrosis for Head and Neck Patients in the IMRT/VMAT Era: Evidence From a Large, Hospital‐Based Cohort

Head &Neck, EarlyView.
ABSTRACT Purpose Osteoradionecrosis (ORN) of the jaw remains a serious late complication of head and neck cancer (HNC) radiotherapy. Although intensity‐modulated radiotherapy (IMRT) and volumetric‐modulated arc radiotherapy (VMAT) are expected to reduce ORN risk, large real‐world data in the modern era are limited.
Fang‐Yu Wu, Hui‐Hsin Ko, Hsiang‐Fong Kao, Shih‐Jung Cheng   +3 more
wiley   +1 more source

Three-Dimensional Dose Prediction for Lung IMRT Patients with Deep Neural Networks: Robust Learning from Heterogeneous Beam Configurations

, 2019
The use of neural networks to directly predict three-dimensional dose distributions for automatic planning is becoming popular. However, the existing methods only use patient anatomy as input and assume consistent beam configuration for all patients in ...
Barragan Montero, Ana Maria, Geets, Xavier, Jiang, Steve, Lin, Mu-Han, Lu, Weiguo, Nguyen, Dan, Norouzi-Kandalan, Roya, Sterpin, Edmond   +7 more
core   +1 more source

IMRT in oral cavity cancer [PDF]

Radiation Oncology, 2007
Abstract Background Except for early T1,2 N0 stages, the prognosis for patients with oral cavity cancer (OCC) is reported to be worse than for carcinoma in other sites of the head and neck (HNC). The aim of this work was to assess disease outcome in OCC following IMRT.
Davis, BJ, Glanzmann, C, Studer, G, Zwahlen, RA, Graetz, KW   +4 more
openaire   +6 more sources

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source