Results 51 to 60 of about 74,991 (297)

Simplifying intensity-modulated radiotherapy plans with fewer beam angles for the treatment of oropharyngeal carcinoma. [PDF]

open access: yes, 2007
The first aim of the present study was to investigate the feasibility of using fewer beam angles to improve delivery efficiency for the treatment of oropharyngeal cancer (OPC) with inverse-planned intensity-modulated radiation therapy (IP-IMRT).
Akazawa, Clayton   +9 more
core   +1 more source

The number of beams in IMRT—theoretical investigations and implications for single-arc IMRT [PDF]

open access: yesPhysics in Medicine and Biology, 2009
The first purpose of this paper is to shed some new light on the old question of selecting the number of beams in intensity-modulated radiation therapy (IMRT). The second purpose is to illuminate the related issue of discrete static beam angles vs. rotational techniques, which has recently re-surfaced due to the advancement of volumetric arc therapy ...
openaire   +3 more sources

Molecular Functions and Drug Prediction of MMP1 and TGFBR2 in Nasopharyngeal Carcinoma

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
MMP1 and TGFBR2 were validated by machine learning and external datasets as the candidate genes. Dexamethasone showed strong binding affinity to MMP1 (−7.72 kcal/mol) and TGFBR2 (−7.27 kcal/mol) in docking studies. Knockdown of MMP1 repressed the malignant phenotypes of NPC cells.
Feng Wang   +5 more
wiley   +1 more source

Study on the transferability of the knowledge-based VMAT model to predict IMRT plans in prostate cancer radiotherapy

open access: yesEuropean Journal of Medical Research, 2023
Objective The aim of this study was to investigate the feasibility of VMAT library-derived model transfer in the prediction of IMRT plans by dosimetry comparison among with three groups of IMRT plans: two groups of automatic IMRT plans generated by the ...
Suyan Bi   +3 more
doaj   +1 more source

Intrafraction motion and impact of margin reduction for MR‐Linac online adaptive radiotherapy for pancreatic cancer treatments

open access: yesJournal of Medical Radiation Sciences, Volume 72, Issue 1, Page 17-24, March 2025.
This analysis included quantification of intrafraction motion in pancreas stereotactic ablative radiotherapy treated on the MR‐Linac, leading to the development of adjusted (PTV) margins. Intrafraction motion indicated an average target displacement of 1–3 mm, resulting in an adjusted PTV margin of 2 mm in the right–left and superior–inferior ...
Ashleigh Fasala   +6 more
wiley   +1 more source

Clinical and dosimetric evaluation of recurrent breast cancer patients treated with hyperthermia and radiation

open access: yesInternational Journal of Hyperthermia, 2019
Background: Treatment for locally recurrent breast cancer poses a significant challenge because the benefits in local control must be weighed against the increased risk of side effects of the treatment.
Sharvari Dharmaiah   +10 more
doaj   +1 more source

Outlier identification in radiation therapy knowledge-based planning: A study of pelvic cases. [PDF]

open access: yes, 2017
PURPOSE: The purpose of this study was to apply statistical metrics to identify outliers and to investigate the impact of outliers on knowledge-based planning in radiation therapy of pelvic cases.
Aggarwal   +23 more
core   +2 more sources

A robust approach to IMRT optimization [PDF]

open access: yesPhysics in Medicine and Biology, 2006
Managing uncertainty is a major challenge in radiation therapy treatment planning, including uncertainty induced by intrafraction motion, which is particularly important for tumours in the thorax and abdomen. Common methods to account for motion are to introduce a margin or to convolve the static dose distribution with a motion probability density ...
Timothy C Y, Chan   +2 more
openaire   +2 more sources

Technique considerations for implementing volumetric‐modulated arc therapy for total body irradiation within an Australian tertiary institution

open access: yesJournal of Medical Radiation Sciences, Volume 72, Issue 1, Page 165-172, March 2025.
In 2020, our institution transitioned to the Eclipse™ treatment planning system and to Truebeam® linear accelerators with 6 MV and 10 MV energies. The linear accelerators were installed in smaller bunkers that could not accommodate 400 cm FAD. A multidisciplinary team within the institution was created to evaluate existing total body irradiation ...
Gabriella La Macchia   +5 more
wiley   +1 more source

Radiotherapy‐Induced Otitis Media With Effusion in Nasopharyngeal Carcinoma: A Meta‐Analysis

open access: yesThe Laryngoscope, EarlyView.
This meta‐analysis of eight studies comprising 582 NPC patients provides the first quantitative synthesis of radiotherapy‐induced otitis media with effusion (OME), demonstrating a significant overall risk difference of 0.18 (95% CI: −0.06 to 0.42, p < 0.0001) in OME naive ears.
Nevin Yi Meng Chua   +3 more
wiley   +1 more source

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