Immunotherapy using pullulan-conjugated Der f 2 allergen in canine atopic dermatitis: An anti-inflammatory agent-sparing approach. [PDF]
Background – Allergen immunotherapy is used as aetiological treatment for canine atopic dermatitis (cAD). Objective – To assess the anti‐inflammatory agent‐sparing effect over 1 year of immunotherapy using pullulan‐conjugated recombinant Der f 2 (rDf2‐P). Conclusions and Clinical Relevance – Der f 2‐P immunotherapy can lead to a rapid reduction in anti‐
Nagata M +7 more
europepmc +2 more sources
Development and immunobiological evaluation of nanoparticles containing an immunodominant epitope of herpes simplex virus. [PDF]
Abstract Herpes simplex virus (HSV) 1 and 2 are viruses that infect individuals worldwide and for which there is no cure or vaccine available. The protective response against herpes is mostly mediated by CD8 T lymphocytes that respond to the immunodominant SSIEFARL epitope.
Hilario GM +10 more
europepmc +2 more sources
Modified rush venom immunotherapy in dogs with Hymenoptera hypersensitivity
Background – Hymenoptera envenomation occurs frequently in people and dogs and can trigger anaphylaxis. Venom immunotherapy (VIT) is the only preventative treatment for Hymenoptera hypersensitivity and is indicated for people with severe adverse reactions to insect stings. Rush VIT is an accelerated VIT induction schedule performed in people.
Alexandra Moore +4 more
wiley +1 more source
The safety of rush immunotherapy in the management of canine atopic dermatitis—230 cases
Background – The duration of the induction phase of allergen‐specific immunotherapy conventionally is a period of several weeks, during which the volume of an allergen solution, administered by injection, is gradually increased until the maintenance dose is reached.
Tamara Weitzer, Ralf Mueller
wiley +1 more source
Abstract Background Allergic skin diseases are common in horses worldwide. The most common causes are insect bites and environmental allergens. Objectives To review the current literature and provide consensus on pathogenesis, diagnosis, treatment and prevention. Materials and Methods The authors reviewed the literature up to November 2022.
R. Marsella +6 more
wiley +1 more source
Background – Atopic dermatitis (AD) is one of the most common skin diseases in small animal practice. Allergen immunotherapy (AIT) is the only curative treatment for the disease, and oral, subcutaneous and intralymphatic administration of allergens are commonly employed.
Ralf S. Mueller +9 more
wiley +1 more source
Efficacy of subcutaneous allergen immunotherapy in atopic dogs: A retrospective study of 664 cases
Background –Canine atopic dermatitis (cAD) is an allergic skin disease affecting approximately 10% of dogs. Allergen immunotherapy (AIT) is currently the only treatment option able to induce tolerance to the causative allergens. Objective – To retrospectively establish the efficacy of AIT in atopic dogs.
Evelien E. M. Fennis +6 more
wiley +1 more source
Immunopathogenesis and immunotherapy of Culicoides hypersensitivity in horses: an update
Culicoides hypersensitivity (CH) is a strongly pruritic dermatitis of horses, characterised histologically by mixed perivascular to diffuse cellular infiltrates of mononuclear cells and eosinophils, and caused by helper T cell (Th)2, immunoglobulin (Ig)E‐mediated reactions to antigens present in the saliva of biting Culicoides midges.
Eliane Marti +7 more
wiley +1 more source
Reproducibility of serum testing for environmental allergen‐specific IgE in dogs in Europe
Background – Serum testing for allergen‐specific immunoglobulin (Ig)E is commonly employed to identify allergens used for allergen‐specific immunotherapy in dogs, yet the reliability of results has been a matter of debate. Objective – The aim of this study was to evaluate the reproducibility of serum tests for environmental allergen‐specific IgE in ...
Katja N. Baumann +4 more
wiley +1 more source
Treatment of the feline atopic syndrome – a systematic review
Background Feline allergic skin disease and asthma occur regularly in small animal practice. Objectives To provide evidence‐based recommendations for small animal practitioners on the treatment of feline atopic syndrome (FAS). Methods and materials The authors reviewed the literature available before February 2020, prepared a detailed evidence‐based ...
Ralf S. Mueller +4 more
wiley +1 more source

