Results 111 to 120 of about 120,811,929 (257)

Reserves, Injury Severity, and Outcomes in Traumatic Brain Injury: A CENTER‐TBI Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Reserve refers to the brain's ability to maintain function after an injury and strongly relates to traumatic brain injury (TBI) outcomes. This study examined (1) whether associations between pre‐injury reserve proxies and outcomes differed across injury severity categories, and (2) whether the impact of injury severity varied across ...
Natascha Ekdahl, Marika C. Möller, Lindsay Wilson, Anne Vik, Toril Skandsen, Jonas Stenberg, CENTER‐TBI participants and investigators   +6 more
wiley   +1 more source

Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez, Fareshte Erani, Katherine J. Bangen, David G. Coughlin, Douglas Galasko, Kelsey R. Thomas   +5 more
wiley   +1 more source

Analysis and Applications of Neuromorphic Memristors in Artificial Intelligence Computing

Nano-Micro Letters
Hightlights Task-oriented perspective on neuromorphic memristors for artificial intelligence computing. From material systems and device structures to applications, flexibility, and system integration.
Jianhui Wang, Qingxin Chen, Jinhao Zhang, Jialin Meng, Tianyu Wang   +4 more
doaj   +1 more source

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source

In-Memory Computing with Memristor Arrays

, 2018
© 2018 IEEE. Memristors with tunable non-volatile resistance states offer the potential for in-memory computing that mitigates the von-Neumann bottleneck.
Yan, Peng, Ge, Ning, Hu, Miao, Williams, R. Stanley, R. Stanley Williams, Belkin, Daniel, J. Joshua Yang, John Paul Strachan, Jiang, Hao, Montgomery, Eric, Qing Wu, Mark Barnell, Barnell, Mark, Can Li, Miao Hu, Li, Yunning, Peng Yan, Ning Ge, Wu, Qing, Daniel Belkin, Xia, Qiangfei, Lin, Peng, Eric Montgomery, Hao Jiang, Zhonguir Wang, Strachan, John Paul, Qiangfei Xia, Peng Lin, Li, Can, Wang, Zhonguir, Yunning Li, Yang, J. Joshua   +31 more
core   +1 more source

Generalized Dystonia With Cervical Predominance in a Patient With a De Novo TCF20 Variant

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT TCF20 has been implicated in developmental delay and intellectual disability, with dystonia reported less frequently. We describe a woman in her early twenties with childhood‐onset learning difficulties, progressive dysarthria, tremor, and generalized dystonia with marked cervical predominance, associated with a de novo TCF20 frameshift ...
Melisa Kilic, Petr Dusek, Ibrahim Kamaci, Bahar Gulmez, Gul Yalcin Cakmakli, Ersin Tan, Sibel Ugur Iseri, Zuhal Yapici   +7 more
wiley   +1 more source

Biomolecular implementation of computing devices with unbounded memory

, 2005
. We propose a new way to implement (general) computing devices with unbounded memory. In particular, we show a procedure to implement automata with unbounded stack memory, push-down au-tomata, using circular DNA molecules and a class IIs restriction ...
Matteo Cavaliere, Nataša Jonoska, Ehud Keinan, Nadrian C. Seeman, Ron Piran, Sivan Yogev, Jonoska N., Cavaliere M., Piran R., Seeman N. C., Yogev S., Keinan E.   +11 more
core   +1 more source

The Association of Amyloid‐β and Tau With Synaptic Dysfunction in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the relative contributions of amyloid and tau to synaptic dysfunction in Alzheimer's disease (AD). Methods We included 109 cognitively unimpaired and impaired individuals from the Geneva Memory Center with available CSF synaptic biomarkers (neurogranin, SNAP‐25, GAP‐43). Participants were stratified according to amyloid (A)
Fausto Roveta, Augusto J. Mendes, Valentina Garibotto, Cecilia Boccalini, Aurelien Lathuiliere, Innocenzo Rainero, Elisa Rubino, Henrik Zetterberg, Nicholas J. Ashton, Federica Ribaldi, Giovanni B. Frisoni, for the Alzheimer's Disease Neuroimaging Initiative   +11 more
wiley   +1 more source

A Two‐Stage Plasma Biomarker Algorithm Reduces Amyloid PET Use and the p‐Tau217 Gray Zone

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐Tau217 leaves 30%–50% of patients in an indeterminate “gray zone” often requiring Aβ‐PET. We developed GRAD (Gatekeeper‐Reflex for Alzheimer's Disease), a two‐stage Aβ‐positivity prediction model to improve classification while reserving Aβ‐PET for residual uncertainty.
Harthik Parankusham, Casey Vanderlip, Colin Birkenbihl, Eashwar Krishna, Chizobam Ugboaja, Andrew E. Budson, Brandon Frank, for the Alzheimer's Disease Neuroimaging Initiative   +7 more
wiley   +1 more source

All Organic Fully Integrated Neuromorphic Crossbar Array

Advanced Electronic Materials
Analog non‐volatile memory devices, such as electrochemical random‐access memory (ECRAM), have emerged as a promising platform for in‐memory computing, facilitating efficient data processing.
Setareh Kazemzadeh, Tim Stevens, Yoeri van de Burgt   +2 more
doaj   +1 more source