Results 191 to 200 of about 115,317,412 (280)

TOP1MT rs2293925 is an enhancer‐active regulatory SNP that shapes mitochondrial R‐loop dynamics

The FEBS Journal, EarlyView.
This study shows how a common genetic variant of mitochondrial topoisomerase 1 (TOP1MT rs2293925) can influence mitochondrial gene regulation, DNA topology, and formation of noncanonical nucleic acid structures such as R‐loops. By linking this enhancer‐active variant to mitochondrial nucleic acid stress in cellular contexts relevant to amyotrophic ...
Dóra Varga, Zsolt Ráduly, Beáta Boros‐Oláh, Éva Nagy, Zsolt Karányi, László Halász, Bálint László Bálint, György Vámosi, Emese Tóth, Péter Bai, Serena Santangelo, Patrizia Bossolasco, Antonia Ratti, Vincent Géli, Yves Pommier, Lóránt Székvölgyi   +15 more
wiley   +1 more source

Yes/No Quantitative Analysis of Single-Stranded Oligonucleotides with Lateral Flow Assays. [PDF]

Biosensors (Basel)
Hassandoost N, Munoz L, Kotecki K, Nesterova IV.   +3 more
europepmc   +1 more source

Comparison of Resistive Index and Volume Flow in Ultrasound of Arteriovenous Fistula for Dialysis Access

Hemodialysis International, EarlyView.
ABSTRACT Introduction Despite extensive investigation, the optimal method of assessing arteriovenous fistula (AV fistula) function remains elusive. Ultrasound is an important tool in the assessment of AV fistula, with a wide range of protocols and flow criteria used across the literature. However, the operator dependency of ultrasound has the potential
Donna L. Oomens, Vincent Lee, Thomas D. Daly, Brendan Winters, Steve Meikle, Jillian Clarke   +5 more
wiley   +1 more source

Structural basis for RISC assembly of human Argonaute2. [PDF]

Mol Cell
Zhang H, Adhav VA, Kehling AC, Savidge A, Shen Z, Fu TM, Nakanishi K.   +6 more
europepmc   +1 more source

First Detailed Record of Jikradia olitoria (Hemiptera: Cicadellidae) in the Swiss Southern Alps and Evaluation of Its Current Potential as a Vector of 16SrV‐Phytoplasmas

Journal of Applied Entomology, EarlyView.
ABSTRACT Jikradia olitoria Say is a Nearctic leafhopper that was recently reported in several European countries. Given its role as the vector of phytoplasmas associated with Grapevine Yellows diseases (GYD) in its native range, its presence in European vineyard agroecosystems could represent an important phytosanitary risk.
Alan Oggier, Christophe Debonneville, Marco Conedera, Attilio Rizzoli   +3 more
wiley   +1 more source

Increased brightness of fluorescent uridine, qU, inside single- and double-stranded RNA. [PDF]

Sci Rep
Karlsson AFE, Pfeiffer P, Le HN, Baladi T, Dahlén A, Wilhelmsson LM.   +5 more
europepmc   +1 more source

Probing the molecular determinants of emission enhancement in RNA aptamer–metal complex systems

Photochemistry and Photobiology, EarlyView.
Light up aptamer: fluorophore pairs are widely used in sensing and imaging, with coordination complex fluorophores providing specific benefits due to their long‐lived emission. Here, we examined key structural and electronic features of these metal complexes to identify the requirements for productive engagement with an RNA aptamer.
Sarah M. Kriger, Joseph Spiconardi, Nathan Ennist, Edith C. Glazer   +3 more
wiley   +1 more source

UV signature mutation hyperhotspots as genomic dosimeters

Photochemistry and Photobiology, EarlyView.
Recurrent UV signature mutations are a sensitive and specific indicator of sun exposure. UV signature mutations (C → T mutations at dipyrimidine sites) were quantified using Duplex Sequencing and a stringent mutation calling protocol to identify true low‐abundance mutations.
Vijay Menon, Alejandro García‐Ruiz, Susan Neveu, Brenda Cartmel, Leah M. Ferrucci, Meg Palmatier, Christine Ko, Kenneth Y. Tsai, Mio Nakamura, Sa Rang Kim, Michael Girardi, Karl Kornacker, Douglas E. Brash   +12 more
wiley   +1 more source

Direct targeting of C9ORF72 repeat RNA with fluorinated antisense oligonucleotides. [PDF]

Nucleic Acids Res
Barber HM, Parasrampuria MA, Jurado-Arjona J, Gamir-Morralla A, Berninger B, González C, Gagnon KT, Damha MJ, Garavís M.   +8 more
europepmc   +1 more source

Optimizing mowing strategies for controlling Lupinus polyphyllus Lindl. in roadside habitats

Restoration Ecology, EarlyView.
Abstract Introduction Road verges provide refuge habitats for semi‐natural grassland species but can also facilitate the spread of invasive alien plant species such as Lupinus polyphyllus Lindl., which negatively impacts biodiversity. Objectives We studied how different mowing regimes affect L.
Elin L. Blomqvist, Daniel Berger, R. Lutz Eckstein   +2 more
wiley   +1 more source