Results 171 to 180 of about 115,317,412 (280)

Cryo-EM structure of a 95-base-pair double-stranded DNA minicircle at 5.3 Å resolution. [PDF]

Nucleic Acids Res
Liu Y, Lee KY, He Y, Kim D, Chang H, Cherezov V, Feigon J, Qin PZ.   +7 more
europepmc   +1 more source

Programmable Assembly of Higher‐Order DNA Nanostructures from Microbial ssDNA Staple Libraries

Small, EarlyView.
A phage‐free, microbial platform produces programmable circular ssDNA libraries that are enzymatically converted into DNA origami staple pools. Rolling‐circle replication generates sequence‐complex ssDNA with >99% fidelity, enabling assembly of DNA tiles and tubules and supporting nanostructure formation even in crude cellular lysates.
Ming Hung Yen, Mallikarjuna Reddy Kesama, Yancheng Du, Jong Hyun Choi, Kevin V. Solomon   +4 more
wiley   +1 more source

Influence of DNA Mispairing and Abasic Sites on Duplex Dynamics: A Temperature-Jump Infrared Spectroscopy Study. [PDF]

J Phys Chem Lett
Hunt NT, Kendall-Price SET, Phelps R, Greetham GM, Burley GA.   +4 more
europepmc   +1 more source

Enhanced through‐bond energy transfer‐based bioorthogonal probe enables catalytic‐amplified and sensitive detection of microRNA‐21 for clinical lung cancer diagnosis

Smart Molecules, EarlyView.
Inverse Diels‐Alder Cycloaddition Reaction was developed for ultrasensitive miR‐21 detection. Based on the enhanced Through‐Bond Energy Transfer and catalytic amplification, it shows a detection limit of 3.58 × 10−18 M and 100 aM–100 nM linear range. It enables high‐contrast cell/tissue imaging and distinguishes lung cancer patients in serum, promising
Yikun Li, Fuping Han, Haiqiao Huang, Danhong Zhou, Saran Long, Wen Sun, Jianjun Du, Jiangli Fan, Jing Ning, Chong Peng, Xiaojun Peng   +10 more
wiley   +1 more source

Structural and Functional Insights Into (S)-5'-C-Guanidinopropyl Uridine-Modified Oligonucleotides With 2'-O-Methyl and 2'-Fluoro Substitutions for RNAi Therapeutics. [PDF]

ChemMedChem
Masaki S, Mahmoud EM, Sakamoto S, Ueno Y.   +3 more
europepmc   +1 more source

Effect of Double Annealing on the Microstructure and Mechanical Properties of a Medium Manganese Steel

steel research international, EarlyView.
A double intercritical annealing strategy is proposed to tailor the multiphase microstructure and mechanical response of a medium‐Mn steel. The treatment produces an ultrafine mixture of ferrite, martensite and multiple austenite populations with graded thermal and mechanical stability, formed through austenite reversion and controlled retransformation.
Mattia Franceschi, Jose A. Jimenez, Carlos Garcia‐Mateo, Radhakanta Rana   +3 more
wiley   +1 more source

Pol γ possesses separate metal binding sites for polymerase and strand displacement functions. [PDF]

Nucleic Acids Res
Baruch-Torres N, Park J, Mora-Garduño J, Roy A, Singh A, Cisneros GA, Brieba LG, Patel SS, Yin YW.   +8 more
europepmc   +1 more source

Near‐Atomic Investigation on the Elemental Redistribution During Coprecipitation of Nano‐Sized Kappa‐Type and B2 Precipitates in an Al‐Alloyed Lightweight Steel

steel research international, EarlyView.
Elemental redistribution during coprecipitation of kappa (κ)‐type and B2 precipitates in an Al‐alloyed lightweight steel is revealed by atom probe tomography (APT) and density functional theory (DFT). Fe and Ni redistribution promotes the evolution of B2 phase from NiAl‐type toward FeAl‐type and improves the stability of κ and B2 phases during ...
Bowen Zou, Yixu Wang, Xiao Shen, Philipp Krooß, Thomas Niendorf, Richard Dronskowski, Wenwen Song   +6 more
wiley   +1 more source

Dual recognition drives site-directed G-quadruplex stabilization: Oligonucleotide design in G4 ligand-oligonucleotide conjugates. [PDF]

Mol Ther Nucleic Acids
Abrahamsson A, Khwaja S, Chaudhari N, Vertueux S, Berner A, Aasumets K, Kumar C, Stietz L, Baladi T, Dahlén A, Wanrooij S, Chorell E.   +11 more
europepmc   +1 more source

Investigation of Serrated Flow in Intercritically Annealed Medium Manganese Steel by In Situ Synchrotron X‐Ray Diffraction

steel research international, EarlyView.
Serrations and stepwise austenite phase transformation were observed in cold‐rolled and annealed medium manganese steels. By in situ XRD experiments, these two phenomena were studied simultaneously. The results show that DSA leads to the creation of PLC bands and load drops in the specimen.
Shahroz Ahmed, Lalit Pun, Matti Isakov, Lassi Raami, Mikko Hokka, Veli‐Tapani Kuokkala, Pasi Peura   +6 more
wiley   +1 more source