Results 171 to 180 of about 101,692 (281)

Prophylactic heminephrectomy for an asymptomatic, non-functioning moiety in pediatric duplex systems: is cancer prevention justified? [PDF]

Front Pediatr
Zhanghuang C, Long N, Yan B.
europepmc   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

The FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin, Sumit Bhutada, Suneel S. Apte   +2 more
wiley   +1 more source

Chemical and photoinduced interstrand crosslinking of oligo DNA duplexes containing 2'-deoxythioguanosines. [PDF]

Commun Chem
Osman JA, Onizuka K, Yamano Y, Nagatsugi F.   +3 more
europepmc   +1 more source

A distinct gene expression mechanism for d‐amino acid utilization in hyperthermophilic archaeon Pyrococcus horikoshii

The FEBS Journal, EarlyView.
The genes PH0137, PH0138, and PH0140 form a cluster in the genome of Pyrococcus horikoshii. The PH0140 gene encodes a transcription factor identified as a d‐amino acid‐responsive regulatory protein (DARP). In feast mode, l‐Ile‐bound DARP binds to the promoter and represses transcription of PH0137 and PH0138. In famine mode, DARP binds to d‐allo‐Ile and
Ryushi Kawakami, Tomoki Kawase, Taira Uehara, Haruhiko Sakuraba, Tomohiko Matsuzawa, Junji Hayashi, Toshihisa Ohshima   +6 more
wiley   +1 more source

Self-Avoiding Gamma Peptide Nucleic Acids for Selective Targeting of RNA Secondary Structures. [PDF]

ACS Chem Biol
Dhami I, Thadke SA, Perera JDR, Batwal R, Zheng E, Thrikawala SW, Aryal B, Ly DH.   +7 more
europepmc   +1 more source

Diagnosing Systemic Mastocytosis: State of the Art

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT With the advent of effective multikinase and selective tyrosine kinase inhibitors in systemic mastocytosis, diagnosing this rare disease has been critical to improving patient morbidity and mortality. This state‐of‐the‐art review interprets the international diagnostic criteria, including differences between the WHO 5th edition classification ...
Anton Rets, Tracy I. George
wiley   +1 more source

An antibody uniquely binding short 2'-O-methyl RNA oligonucleotide duplexes: formation and recognition of target duplexes on cell surfaces. [PDF]

Front Immunol
Dunn IS, Lawler MM, Fagundes L, Simoes Junior M, Mangold A, Rinaldi D, Rose LB, Kurnick JT.   +7 more
europepmc   +1 more source

Unity or Distinction? Herman Bavinck’s Use of John Calvin and Later Reformed Orthodoxy in His Doctrine of the Two States

International Journal of Systematic Theology, EarlyView.
Abstract This article examines the doctrine of Christ’s two states of humiliation and exaltation in Herman Bavinck’s and John Calvin’s thought, with the aim of illuminating Bavinck’s use of Calvin. The article begins by exploring Calvin’s use of the two states and argues that his treatment of Christ’s descent into hell is an important though ...
Sarah Killam Crosby
wiley   +1 more source

Zinc-finger transcription factor Fzf1 binds to its target DNA in a non-canonical manner. [PDF]

Nucleic Acids Res
Ma C, Du Y, Xiao W, Moore SA.
europepmc   +1 more source

Alloxazine derivatives as multifunctional agents for photodynamic therapy, cancer cell imaging, and cell proliferation inhibition

Photochemistry and Photobiology, EarlyView.
Alloxazine photosensitizers, molecularly engineered through sugar conjugation and methoxy substitution to enhance solubility, photodynamic potency, and fluorescence, enable image‐guided photodynamic therapy while inhibiting cancer cell growth in the absence of photoactivation.
Rubej R. Khan, Sourav Kanti Seth, Reshma Mathew, Nitza V. Falcón‐Cruz, Chris Acquah, Steffen Jockusch, Liraz Levi, Carlos E. Crespo‐Hernández   +7 more
wiley   +1 more source