Results 201 to 210 of about 115,317,412 (279)

UV signature mutation hyperhotspots as genomic dosimeters

Photochemistry and Photobiology, EarlyView.
Recurrent UV signature mutations are a sensitive and specific indicator of sun exposure. UV signature mutations (C → T mutations at dipyrimidine sites) were quantified using Duplex Sequencing and a stringent mutation calling protocol to identify true low‐abundance mutations.
Vijay Menon, Alejandro García‐Ruiz, Susan Neveu, Brenda Cartmel, Leah M. Ferrucci, Meg Palmatier, Christine Ko, Kenneth Y. Tsai, Mio Nakamura, Sa Rang Kim, Michael Girardi, Karl Kornacker, Douglas E. Brash   +12 more
wiley   +1 more source

Direct targeting of C9ORF72 repeat RNA with fluorinated antisense oligonucleotides. [PDF]

Nucleic Acids Res
Barber HM, Parasrampuria MA, Jurado-Arjona J, Gamir-Morralla A, Berninger B, González C, Gagnon KT, Damha MJ, Garavís M.   +8 more
europepmc   +1 more source

Optimizing mowing strategies for controlling Lupinus polyphyllus Lindl. in roadside habitats

Restoration Ecology, EarlyView.
Abstract Introduction Road verges provide refuge habitats for semi‐natural grassland species but can also facilitate the spread of invasive alien plant species such as Lupinus polyphyllus Lindl., which negatively impacts biodiversity. Objectives We studied how different mowing regimes affect L.
Elin L. Blomqvist, Daniel Berger, R. Lutz Eckstein   +2 more
wiley   +1 more source

A Target-Displaced Aptamer-cDNA Duplex Strategy on ERGO for Ultrasensitive Turn-On Electrochemical Detection of Ochratoxin A. [PDF]

Sensors (Basel)
Lestari IG, Jang SJ, Kim TH.
europepmc   +1 more source

Increases in skin perfusion and blood oxygen in the non‐exercising human limbs during exercise in the heat: Implications for control of circulation

Experimental Physiology, EarlyView.
Abstract Blood flow in the inactive limb tissues and skin is widely thought to decline during incremental exercise to exhaustion due to augmented sympathoadrenal vasoconstrictor activity, but direct evidence to support this view is lacking. Here, we investigated the inactive‐forearm haemodynamic (Q̇forearm${\dot{Q}}_{\mathrm{forearm}}$) and oxygenation
Steven J. Trangmar, José González‐Alonso   +1 more
wiley   +1 more source

Vascular, inflammatory and perceptual responses to hot water immersion: Impacts of water depth and temperature in young healthy adults

Experimental Physiology, EarlyView.
Abstract Repeated hot water immersion can improve cardiovascular health; however, the respective effects of distinct immersion protocols remain unclear. Twenty‐two healthy adults completed three 30‐min hot water immersion bouts of different water temperatures and immersion depths (40°C shoulder‐deep immersion, 40‐Shoulder; 42°C waist‐deep immersion, 42‐
Campbell Menzies, Neil D. Clarke, Charles J. Steward, Charles Douglas Thake, Christopher J. A. Pugh, Tom Cullen   +5 more
wiley   +1 more source

Cerebral haemodynamic responses to inspiratory muscle work

Experimental Physiology, EarlyView.
Abstract Fatiguing inspiratory work has been shown to evoke a sympathetically mediated reflex that has systemic cardiovascular consequences, including increases in heart rate and blood pressure and a decrease in resting limb vascular conductance. Moreover, the response to this reflex appears to be attenuated in females compared with males.
Andrew H. Ramsook, Morgan A. Hughes, Wyatt W. Pruter, Kevin L. Webb, Ali Ataie, Chad C. Wiggins, Gabrielle A. Dillon, Sarah E. Baker, Michael J. Joyner   +8 more
wiley   +1 more source

Vascular and Neural Compression Syndromes Associated with Plantaris Muscle Variants: A Classification-Based Review. [PDF]

J Clin Med
Olewnik Ł, Landfald IC, Łapot M, LaPrade RF.   +3 more
europepmc   +1 more source

Carotid artery dissection linked to intermittent apnoeic swimming: A case–control study

Experimental Physiology, EarlyView.
Abstract Internal carotid artery (ICA) dissection is a rare and potentially devastating cause of cerebral ischaemia, initiated by an intimal tear or rupture of the vasa vasorum, that can lead to an intraluminal thrombus, vascular stenosis, occlusion, or dissecting aneurysm formation.
Damian M. Bailey, Richard G. Davies, Brenig L. Gwilym, Benjamin S. Stacey, Danny Walmsley, Michael H. Lewis, Josip Butkovic, Ivan Mumlek, Brad Perry, Zvonomir Vrselja, Shigehiko Ogoh, James A. Pawelczyk, Mohamad Bashir, Richard D. White, Ian M. Williams   +14 more
wiley   +1 more source

Molecular basis of UV lesion binding and repair inhibition by ETS-family transcription factors. [PDF]

Nucleic Acids Res
Sivapragasam S, Terrell JR, van der Vaart A, Germann MW, Laughery MF, Everly ME, Adhikari SP, Hrdlicka PJ, Wyrick JJ, Poon GMK.   +9 more
europepmc   +1 more source