Results 201 to 210 of about 473,642 (344)
ABSTRACT The rising incidence of chronic diseases globally has drawn widespread attention to phytochemicals, which exert targeted preventive and alleviating effect by modulating gut microbiota; thus, a potential strategy for precision nutritional interventions is offered.
Shiqi Bai +6 more
wiley +1 more source
Cosmetic after-feel modulates brain activity in sensory and reward networks: an fMRI study. [PDF]
Maniere A +5 more
europepmc +1 more source
Current understanding of Merkel cells, touch reception and the skin [PDF]
Zdeněk Halata +2 more
openalex +1 more source
Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang +10 more
wiley +1 more source
Dysfunctional neural dynamics associated with sensory phenotypes in Fragile X syndrome: insights from mouse models. [PDF]
Goel A +3 more
europepmc +1 more source
Ng et al. show that the BCR::ABL1 kinase that drives the lymphoid leukemia Ph+B‐ALL modulates enhancer function by coopting signaling‐inducible transcription factors such as MYC, STAT5, and ETV5. BCR::ABL1 thereby promotes the transcriptional program driving and defining this leukemia and renders Ph+B‐ALL cells hypersensitive to enhancer‐inhibiting ...
Han Leng Ng +19 more
wiley +1 more source
Impaired touch sensation on hairy skin in HCN3-deficient mice. [PDF]
Metzner K +5 more
europepmc +1 more source
Lamellar cells in Pacinian and Meissner corpuscles are touch sensors
Yury A. Nikolaev +5 more
openalex +1 more source
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang +10 more
wiley +1 more source

