Engineered mesoporous silica nanoparticles (Silicasomes) enable systemic delivery of the STING agonist ADU‐S100, overcoming the instability and toxicity that limit cyclic dinucleotides to local administration. By enhancing tumor accumulation, activating systemic antitumor immunity, and remodeling the tumor immune microenvironment, these nanoparticles ...
Wenjing Zhou +10 more
wiley +1 more source
Integrating MACSPI and SILAC for Neuron Type-specific Proteomics in Caenorhabditis elegans. [PDF]
Ran Q, Huang S, Li XD, Zheng C.
europepmc +1 more source
Simply constructed polyvinylpyrrolidone (PVP) modified palladium nanoparticles (PdP NPs) as cytochrome c oxidase (CcO) and superoxide dismutase (SOD) mimic are promising multifunctional nanoreactors to boost mitochondrial respiration chain function and refine homeostasis via regulation of mitochondrial dynamics and proteostasis sensor UPRmt, which ...
Wenshu Cong +8 more
wiley +1 more source
Feel it to learn it!-Cognitive and motivational effects of haptic learning materials. [PDF]
Erdmann HS +3 more
europepmc +1 more source
Ion‐Pair‐Tuned Ionogels for Broad‐Range Linear Pressure Sensing
Ionogels engineered through ion‐pair tuning extend the linear sensing range of capacitive pressure sensors. By balancing ionic mobility and polarizability within the polymer matrix, this approach mitigates dielectric saturation and maintains a stable pressure response across a broad operating range.
Hyeonseo Joo +11 more
wiley +1 more source
SIR-2.3/SIRT4 loss enhances proteostasis and neuronal resilience via AMPK-induced autophagy in Huntington's disease models. [PDF]
Trujillo-Del Río C +13 more
europepmc +1 more source
Two Seven-Transmembrane Domain MILDEW RESISTANCE LOCUS O Proteins Cofunction in Arabidopsis Root Thigmomorphogenesis [PDF]
Chen, Z. +9 more
core
Bio‐templated Piezoresistive Yarn for High Sensitivity Movement Monitoring Textiles
This study developed a conductive coating by biotemplating silver nanoparticles (AgNPs) onto a Potato virus A (PV) particle network, cross‐linked on co‐polyamide‐starch (CoPA‐SS) coils. The combination of CoPA‐SS's shape memory and PV‐AgNP's piezoresistivity achieved high strain sensitivity and minimal hysteresis.
Swarnalok De +10 more
wiley +1 more source
Capacitance Characteristics of Glass-Embedded Interdigitated Capacitors for Touch Sensing Applications. [PDF]
Kaewcharoen A +4 more
europepmc +1 more source
Ethical Precision in Nanoscale Brain Interfacing
As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley +1 more source

