Results 111 to 120 of about 1,063,217 (316)

A performance study of big data workloads in cloud datacenters with network variability

, 2018
Public cloud computing platforms are a cost-effective solution for individuals and organizations to deploy various types of workloads, ranging from scientific applications, business-critical workloads, e-governance to big data applications.
Uta, Alexandru, Uta, Alexandru; id_orcid, Obaseki, Harry, Harry Obaseki, Alexandru Uta   +4 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Cloud Computing as Network Environment in Students Work [PDF]

, 2013
The purpose of the paper is to show the need for literacy education from a variety of services available in the cloud computing as a specialist information field of activity.
Dominik Mirosław Piotrowski, Piotrowski, Dominik Mirosław   +1 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

An Efficient Internet-Wide Scan Approach Based on Location Awareness

Future Internet
With increasing network security threats, Internet-wide scanning has become a key technique for identifying network vulnerabilities. However, traditional scanning methods tend to ignore the impact of geographic factors on scanning efficiency.
Wenqi Shi, Huiling Shi, Hao Hao, Qiuyu Guan   +3 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Federated Transfer Learning for On-Device LLMs Efficient Fine Tuning Optimization

Big Data Mining and Analytics
The proliferation of Large Language Models (LLMs) has catalyzed the growth of various industries. It is therefore imperative to ensure the controlled and beneficial application of LLMs across specific domains for downstream tasks through transfer ...
Chuantao Li, Bruce Gu, Zhigang Zhao, Youyang Qu, Guomao Xin, Jidong Huo, Longxiang Gao   +6 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Security analysis and monitoring assessment of networked printers: A report

Electronics Letters
In this letter, a comprehensive and detailed introduction to the current security risks faced by networked printers is given, the security monitoring platform and attack detection method are explained, and the actual monitoring results are analyzed.
Quanbo Pan, Shengbao Li, Na Li, Peiying Zhang, Lizhuang Tan   +4 more
doaj   +1 more source

Execution Plans for Serverless Computing in Information Centric Networking

, 2019
Information Centric Networking (ICN) is a modern networking concept which enables users to address named data directly by their name, without knowing the location where the data is stored. Since requesting static data is only a special case of requesting
Tschudin, Christian, Christopher Scherb, Scherb, Christopher, Marxer, Claudio, Christian Tschudin, Claudio Marxer   +5 more
core   +1 more source