Results 131 to 140 of about 1,063,217 (316)

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Computational Sensor Networks [PDF]

2007 IEEE/RSJ International Conference on Intelligent Robots and Systems, 2009
Thomas C. Henderson, Christopher A. Sikorski, Edward Grant, Kyle Luthy   +3 more
openaire   +2 more sources

Trajectory Prediction and Decision Optimization for UAV-Assisted VEC Networks: An Integrated LSTM-TD3 Framework

Information
With the rapid development of intelligent transportation systems (ITSs) and Internet of Things (IoT), vehicle-mounted edge computing (VEC) networks are facing the challenge of handling increasingly growing computation-intensive and latency-sensitive ...
Jiahao Xie, Hao Hao
doaj   +1 more source

Network and Parallel Computing [PDF]

International Journal of Parallel Programming, 2014
Ching-Hsien Hsu, Valentina Salapura
openaire   +1 more source

Government cloud computing and the policies of data sovereignty [PDF]

Government cloud services are a new development at the intersection of electronic government and cloud computing which holds the promise of rendering government service delivery more effective and efficient.
Irion, Kristina
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Decoupled knowledge distillation method based on meta-learning

High-Confidence Computing
With the advancement of deep learning techniques, the number of model parameters has been increasing, leading to significant memory consumption and limits in the deployment of such models in real-time applications.
Wenqing Du, Liting Geng, Jianxiong Liu, Zhigang Zhao, Chunxiao Wang, Jidong Huo   +5 more
doaj   +1 more source

Computing News ; vol. 03, no. 01 (October 1987)

, 1987
4 p.Welcome to Computing at the U of O -- New Network to Link Northwest -- New Computer System on the Way -- Computing Reorganization -- Computing Center Renovations -- Campus-Wide Network Plans -- Education Program Offerings -- Documents Room Services --
Winslow, Joyce, University of Oregon. Computing Center   +1 more
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Supporting simulation in industry through the application of grid computing

, 2008
An increased need for collaborative research, together with continuing advances in communication technology and computer hardware, has facilitated the development of distributed systems that can provide users access to geographically dispersed computing ...
Simon J. E. Taylor, HASH(0x55a67fa81c60), Mustafee, N, Navonil Mustafee, Mustafee, Navonil, Taylor, S J E, Taylor, Simon J. E.   +6 more
core   +1 more source