Results 61 to 70 of about 114,629,556 (343)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Inversion of In-situ stress field in near-fault coal mining area by coupling numerical simulation with deep learning

Geomatics, Natural Hazards & Risk
Understanding the in-situ stress distribution is crucial for coal mine production. In mining area 105 of Yuandian No. 1 Coal Mine, in-situ stress measurements were carried out using the stress relief method.
Rongqin Deng, Yuan Zhang, Dong Wu, Jiakun Lv, Yanan Jing, Zheng Zhen, Peng Shi   +6 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Susceptibility assessment of geological hazards in Shenzhen Town, Ninghai county based on the APH-CF model

Frontiers in Earth Science
IntroductionThis work employs a coupled evaluation model that integrates deterministic coefficients with the Analytic Hierarchy Process to conduct a comprehensive assessment of geological disaster susceptibility in Shenzhen Town, Ninghai County ...
Shuai Han, Ran Li, Ran Li, Ran Li, Shujun Hui, Qiang Sun, Taili Zhang   +6 more
doaj   +1 more source

Advances in martensitic transformations in Cu-based shape memory alloys achieved by in situ neutron and synchrotron X-ray diffraction methods [PDF]

, 2012
This article deals with the application of several X-ray and neutron diffraction methods to investigate the mechanics of a stress induced martensitic transformation in Cu-based shape memory alloy polycrystals. It puts experimental results obtained by two
Sophie Berveiller, Benoit Malard, Etienne Patoor, Petr Sittner, Berveiller, Sophie, Patoor, Etienne, Malard, Benoît, Sittner, Petr   +7 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

3D displacement discontinuity analysis of in-situ stress perturbation near a weak faul

Advances in Geo-Energy Research, 2021
A numerical investigation utilizing the 3D displacement discontinuity method is performed to examine the stress perturbations and induced displacements near a weak fault with arbitrary orientations and dip, assuming zero shear stress and normal ...
Yutong Chai, S. Yin
semanticscholar   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Minimum stress and pore fluid pressure in sedimentary basins [PDF]

, 2001
Leak-off pressures (LOPs) recorded during leak-off tests (LOTs) conducted down boreholes are often used to estimate the magnitude of the minimum stress (usually assumed to be horizontal – S(_h)) in the subsurface.
White, Adrian James
core