Results 61 to 70 of about 388,680 (332)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Research on In Situ Stress Measurement Based on the Combined Method of DIC and Drilling Stress Relief

Buildings
Existing structural stress is an important parameter for evaluating the current state of a structure. In order to improve the accuracy of in situ stress measurement in the field, this paper proposes an in situ stress measurement method for existing ...
Lingting Ye, Liping Chen, Peng Zhao, Ruichuan Zhao, Yixiang Zhou   +4 more
doaj   +1 more source

In situ observation of strain and phase transformation in plastically deformed 301 austenitic stainless steel [PDF]

, 2016
To inform the design of superior transformation-induced plasticity (TRIP) steels, it is important to understand what happens at the microstructural length scales.
Abreu, Bachmann, Bain, Bhadeshia, Bhadeshia, Bolling, Bouguet, Bowles, Bunge, Cakmak, Chatterjee, Cherkaoui, Clocksin, Delogu, Di Gioacchino, Dieter, Ferreira, Frank, Geijselaers, Gey, Gioacchino, Guimarães, Kammers, Kato, Kundu, Kundu, Kundu, Kurdjumov, LaVision, Lecroisey, Lim, Lucas, Mackenzie, McMurtrey, Moat, Olson, Olson, Olson, Patel, Patriarca, Roters, Sachs, Schreier, Simm, Simm, Sutton, Takahashi, Talonen, Talonen, Tasan, Taylor, Tsuchida, Tsuchida, Yeddu, Zackay   +54 more
core   +2 more sources

A theory of rock core-based methods for in-situ stress measurement

, 2009
The behavior of the inelastic strain of rocks under the loading of compression reflects the history of stresses applied to the rocks. A number of methods based on this rock property of stress memory have been proposed for measuring in-situ stress.
Kiyohiko Yamamoto
semanticscholar   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Research on the correction method of hydraulic fracturing in-situ stress testing based on MLP-KFold [PDF]

Geoscientific Instrumentation, Methods and Data Systems
Hydraulic fracturing serves as a critical in-situ stress testing technique, where the accurate determination of rock fracture pressure and closure pressure in fracturing intervals is essential for precise in-situ stress estimation.
Y. Liu, J. Zhou, H. Chen, J. Luo, J. Luo
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

In-situ stress conditions at Nankai Trough, Site 808 [PDF]

, 1993
Shipboard laboratory index property data, shore-based consolidation tests, and in-situ stress and pore-pressure measurements are used in this study to constrain the stress conditions at ODP Site 808, Nankai Trough.
Brückmann, Warner, Campanella, R. G., Feeser, Volker, Moran, K.   +3 more
core  

Real-time depth sectioning: Isolating the effect of stress on structure development in pressure-driven flow [PDF]

, 2009
Transient structure development at a specific distance from the channel wall in a pressure-driven flow is obtained from a set of real-time measurements that integrate contributions throughout the thickness of a rectangular channel. This “depth sectioning
Derek W. Thurman, Eder G., Fuller G. G., Fuller G. G., Janeschitz-Kriegl H., Julia A. Kornfield, Keller A., Liedauer S., Lucia Fernandez-Ballester, Roe R. J.   +9 more
core   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source