Results 181 to 190 of about 167,809 (296)

Moving forward through the in silico modeling of multiple sclerosis: Treatment layer implementation and validation. [PDF]

Comput Struct Biotechnol J, 2023
Maleki A, Crispino E, Italia SA, Di Salvatore V, Chiacchio MA, Sips F, Bursi R, Russo G, Maimone D, Pappalardo F.   +9 more
europepmc   +1 more source

Large‐Scale Genomics Reveals Three‐Source Ancestry and Layered Adaptation to High Altitude in Tibetan Chickens

Advanced Science, EarlyView.
Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao, Ruixue Nie, Hailu Fan, Tenzin Ngodroup, Li Zhu, Hongbin Pan, Bo Zhang, Hao Zhang   +7 more
wiley   +1 more source

In silico modeling-based new alternative methods to predict drug and herb-induced liver injury: A review. [PDF]

Food Chem Toxicol, 2023
Shin HK, Huang R, Chen M.
europepmc   +1 more source

In Silico Modeling: the Human Factor

Humana.Mente: Journal of Philosophical Studies, 2016
Bertolaso, Marta, MacLeod, Miles Alexander James   +1 more
openaire   +2 more sources

A Nanobody‐LNP Platform for Targeting and Relicensing Dendritic Cells for Potent Cancer Immunotherapy

Advanced Science, EarlyView.
Plastin‐2 (PLS2) is identified as a dual‐function receptor on DCs that mediates both nanoparticle uptake and immunomodulation. A nanobody‐LNP platform is engineered to integrate antigen delivery with relicensing DCs. The therapeutic strategy elicits potent anti‐tumor T cell responses and leads to significant inhibition of established tumors in vivo ...
Shugang Qin, Zhiying Huang, Hai Huang, Yupei Zhang, Yuting Chen, Xi He, Zhenyi Niu, Zhongzheng Xiang, Chaoyu Zou, Xiangrong Song   +9 more
wiley   +1 more source

In Silico Modeling of Safe Force Limits for Trismus Therapy Following Jaw Reconstruction. [PDF]

Head Neck
Mohseni-Dargah M, Wan B, Charters E, Dunn M, Manzie T, Aung YM, Hasmat S, Li Q, Clark JR.   +8 more
europepmc   +1 more source

In Silico Modeling for Ex Vivo Placental Transfer of Morphine. [PDF]

J Clin Pharmacol, 2022
Ho H, Zhang S, Kurosawa K, Chiba K.
europepmc   +1 more source

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

Advanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv, Yi Liu, Ning Xu, Xiao Zhang, Yaming Yang, Chengyao Li, Hanhai Mao, Mingyuan Liu, Xiaolei Liu   +8 more
wiley   +1 more source

Characterizing cyanopeptides and transformation products in freshwater: integrating targeted, suspect, and non-targeted analysis with in silico modeling. [PDF]

Anal Bioanal Chem
Roy-Lachapelle A, Solliec M, Gagnon C.
europepmc   +1 more source

Toward in Silico Modeling of Dynamic Combinatorial Libraries. [PDF]

ACS Cent Sci, 2022
Casciuc I, Osypenko A, Kozibroda B, Horvath D, Marcou G, Bonachera F, Varnek A, Lehn JM.   +7 more
europepmc   +1 more source