Results 91 to 100 of about 5,765,502 (356)

Mechanics and Permeability Evolution Mechanism of Bedded Sandy Mudstone under Fluid-Solid Coupling Action

Taiyuan Ligong Daxue xuebao
[Purposes] In order to better understand the permeability changes of coal measure bedded sandy mudstone under stress, the mechanical characteristics and permeability of bedded sandy mudstone were studied by discrete element simulation on the basis of the
LIU Xinyu, CHAI Zhaoyun, XIN Zipeng, XIAO Chang, LIU Xiangyu, LI Tianyu, YAN Ke, DUAN Biying   +7 more
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Creep damage model for deep salt rock under temperature and stress coupling effect

Meitan xuebao
As the demand on the construction salt rock storage increases in China, the shallow suitable deposits have been gradually exhausted, as such, the utilization shift from shallow to deep salt deposits is an inevitable trend.
Shengli ZHANG, Suguo XU, Ning XIAO, Jing LI, Chao LI   +4 more
doaj   +1 more source

Status And Recommendations For In situ Anoa (Bubalus SP.) With Suggested Implications For The Conservation Breeding Population (Status dan Rekomendasi Anoa (Bubalus SP.) In situ dengan Implikasi untuk Konservasi Populasi Berbiak) [PDF]

, 2007
Ringkasan ini menguraikan status konservasi in situ kerbau kerdil Sulawesi. Trend populasi yang dilaporkan dalam dua belas tahun terakhir mengarahkan penulis dalam menyoroti arti penting konservasi populasi berbiak di lokasi ex situ pada masa mendatang ...
Burton, J. (JA), Macdonald, A. (Alastair), Mustari, A. (AH)   +2 more
core  

In situ analysis for intelligent control [PDF]

, 2007
We report a pilot study on in situ analysis of backscatter data for intelligent control of a scientific instrument on an Autonomous Underwater Vehicle (AUV) carried out at the Monterey Bay Aquarium Research Institute (MBARI).
Fox, M., Long, D., Py, F., Rajan, K., Ryan, J.   +4 more
core   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Planning the integration of ex situ plant conservation in Tasmania [PDF]

, 2013
Tasmania has a strong record of successful in situ plant conservation but there will always be a role for the integration of various ex situ measures into a plant conservation program due to pressure by threatening processes on wild populations.
Crane, Nepelle, Harris, Stephen, Shaw, Justine   +2 more
core  

Protein crystallization and structure determination at room temperature in the CrystalChip

FEBS Open Bio, Volume 15, Issue 4, Page 532-541, April 2025.
This protocol describes the implementation of a simple and user‐friendly microfluidic device called CrystalChip that allows the production of crystals by the counter‐diffusion method and their in situ analysis by serial crystallography. As an illustration, it is applied to determine the 3D structure of three proteins from data collected at room ...
Petr Pachl, Léna Coudray, Romain Vincent, Léa Nilles, Hélène Scheer, Christophe Ritzenthaler, Adéla Fejfarová, Pavlína Řezáčová, Sylvain Engilberge, Claude Sauter   +9 more
wiley   +1 more source

Understanding the Impact of Synchronous, Asynchronous, and Hybrid In-Situ Techniques in Computational Fluid Dynamics Applications [PDF]

High-Performance Computing (HPC) systems provide input/output (IO) performance growing relatively slowly compared to peak computational performance and have limited storage capacity. Computational Fluid Dynamics (CFD) applications aiming to leverage the full power of Exascale HPC systems, such as the solver Nek5000, will generate massive data for ...
arxiv   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source