Results 101 to 110 of about 33,947 (245)

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

open access: yesAdvanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang   +11 more
wiley   +1 more source

A microbial electrochemical system enables the energy-efficient conversion of cyanobacterial biomass into plant fertilizer for Mars

open access: yesChemical Engineering Journal Advances
Producing significant amounts of food on Mars will be challenging, as crops could not grow solely on local resources. One promising solution lies in first cultivating cyanobacteria using Martian regolith, sunlight, water, and atmospheric gases (N₂, CO₂),
Tiago P Ramalho   +5 more
doaj   +1 more source

Programmable Encapsulation Enables On‐Demand Proliferation of Therapeutic Bacteria for Potent Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A programmable encapsulation technology is developed to reduce bacterial immunogenicity and proliferation after systemic administration. The cross‐linked polymer networks around individual bacteria enable immunogenic shielding and permit selective proliferation in tumors, allowing the bacteria to convert tumor‐accumulated ammonia into L‐arginine and ...
Jianhui Yang   +12 more
wiley   +1 more source

In situ biomass estimation of cultivated kelp using RGB imagery

open access: yes, 2023
Global produksjon i makroalgeoppdrett utgjør over en fjerdedel av total oppdrettsproduksjon, med et produksjonsvolum på opptil 35.1 millioner tonn i 2020. I Norge er det stadig økt innsats for å utvikle makroalgeoppdrett til en ny bioøkonomi. Produksjon er basert på to tarearter, Saccharina latissima og Alaria esculenta, grunnet deres høye vekstrater ...
openaire   +1 more source

Adaptive Responses of Tropical Crops: A Multi‐Scale Omics Integrated Perspective

open access: yesAdvanced Science, EarlyView.
Tropical crops integrate genomic, morphological, physiological, and ecological adaptations to thrive under extreme and variable environments. This review highlights how natural selection, domestication, and breeding shape stress resilience, resource‐use strategies, and productivity in sugarcane, banana, cassava, rubber and oil palm, offering new routes
Peilin Wang   +11 more
wiley   +1 more source

Cultivation of Chroococcidiopsis thermalis Using Available In Situ Resources to Sustain Life on Mars

open access: yesLife
The cultivation of cyanobacteria by exploiting available in situ resources represents a possible way to supply food and oxygen to astronauts during long-term crewed missions on Mars. Here, we evaluated the possibility of cultivating the extremophile cyanobacterium Chroococcidiopsis thermalis CCALA 050 under operating conditions that should occur within
Giacomo Fais   +9 more
openaire   +3 more sources

Miro1 Protects Against Acute Kidney Injury Through Modulating Mitochondrial Homeostasis via Interaction With Sirt6

open access: yesAdvanced Science, EarlyView.
Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu   +12 more
wiley   +1 more source

Estimation of nitrifying capacity in corn cultivated soils by incubation in situ

open access: yes, 1987
Incubations under field conditions in cylindres had been made, in order to maintain soil's structure, covering them with polyethylene bags preventing N-loss by leaching. Soils belonging to the center of the Argentine corn area were used during the months of January and February (Cropping season 1982/83 and 1983184).
Zourarakis, Demetrio   +3 more
openaire   +1 more source

Chemical‐Biological Fixation for Enhanced Bone Augmentation in Guided Bone Regeneration

open access: yesAdvanced Science, EarlyView.
M2N2ACa is an innovative injectable thermoresponsive barrier membrane adhesive to achieve reliable bone graft fixation. It provides strong wet adhesion and promotes the bio‐stabilization mediated by coagulation through controlled calcium release. This dual‐fixation strategy combines external chemical fixation and internal biological fixation via clot ...
Yu‐zhu Wang   +13 more
wiley   +1 more source

Overcoming Transmission Barriers: A Dual‐Functional Adhesive Hydrogel for Direct Monkeypox Virus Neutralization and Wound Healing

open access: yesAdvanced Science, EarlyView.
MPXV infection leads to persistent viral replication and severe local inflammation, while existing treatments cannot simultaneously remove viruses and repair injured tissue. This study constructs Polymer@mPDA@Gel hydrogel via a two‐step hierarchical assembly method: mPDA anchors photothermal polymers to form antiviral photothermal subunits, which are ...
Ming Zhang   +7 more
wiley   +1 more source

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