Results 91 to 100 of about 26,404 (336)

Pericyte-mediated regulation of capillary diameter: a component of neurovascular coupling in health and disease [PDF]

, 2010
Because regional blood flow increases in association with the increased metabolic demand generated by localised increases in neural activity, functional imaging researchers often assume that changes in blood flow are an accurate read-out of changes in ...
Attwell, D., Hall, C.N., Hamilton, N.B.
core   +3 more sources

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

Angiogenesis in tissue engineering : Breathing life into constructed tissue substitutes [PDF]

, 2006
Long-term function of three-dimensional (3D) tissue constructs depends on adequate vascularization after implantation. Accordingly, research in tissue engineering has focused on the analysis of angiogenesis.
Amon, Michaela, Carvalho, Carlos, Farhadi, Jian, Germann, Gunter, Haeufel, Joerg M., Harder, Yves, Heberer, Michael, Junker, Dominic, Laschke, Matthias W., Martin, Ivan, Menger, Michael D., Ring, Andrej, Ruecker, Martin, Schramm, Rene, Torio-Padron, Nestor, Vollmar, Brigitte   +15 more
core   +1 more source

Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring

Advanced Science, EarlyView.
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang, Xin Zhou, Min Liu, Meimei Huang, Peirong Chen, Xinying Li, Fangchao Xue, Wenyan Zhao, Di Liu, Lang Li, Yuangang Lu, Wen Zeng   +11 more
wiley   +1 more source

Effects of Morinda citrifolia Leaf Extract on Glucose Absorption through Intestinal Epithelial Membrane in Wistar Rat Models

Althea Medical Journal, 2017
Background: Noni fruit (Morinda citrifolia) has been used as herbal medicine by Indonesian people. However, the effect of noni leaves as an antihyperglycemic agent is still unknown.
Rikho Melga Shalim, Mas Rizky A. A. Syamsunarno, Muhammad Nurhalim Shahib   +2 more
doaj   +1 more source

Intestinal Absorption Mechanisms of Five Flavonoids from Malus hupehensis (Pamp.) Rehd. Extracts in Situ Single-Pass Intestinal Perfusion and in Vitro Caco-2 Cell Model [PDF]

, 2020
Hui Yang, Zhishu Tang, Jiangxue Cheng, Jing Wang, Junbo Zou, Xiaofei Zhang, Yajun Shi, Dongyan Guo   +7 more
openalex   +1 more source

CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human

Advanced Science, EarlyView.
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan, Jiafu Li, Min Shao, Haili Bao, Ajun Geng, Jialin Yang, Yu Tao, Xinyi Chen, Tianxiong Xiao, Chunye Liu, Zhiyao Xie, Wenqian Song, Qing Cissy Yu, Hongxing Fu, Xu Han, Taochen He, Wenquan Wang, Jianfeng Chen, Sheng Yan, Shaohua Song, Liang Liu, Yi Arial Zeng   +21 more
wiley   +1 more source

Studies on the antidiabetic effects of Mangifera indica stem-barks and leaves on nondiabetic, type 1 and type 2 diabetic model rats

Bangladesh Journal of Pharmacology, 2009
Mangifera indica Linn, locally known as mango tree has been claimed to possess antidiabetic properties by many investigators. The present study was undertaken to screen the hypoglycemic and antihyperglycemic activity of both ethanol and water extracts of
Amrita Bhowmik, Liakot Ali Khan, Masfida Akhter and Begum Rokeya
doaj   +2 more sources

Formulation design, characterization, and in vitro and in vivo evaluation of nanostructured lipid carriers containing a bile salt for oral delivery of gypenosides

International Journal of Nanomedicine, 2019
Gang Yang, Feihua Wu, Minyan Chen, Jian Jin, Rong Wang, Yongfang Yuan Department of Pharmacy, Shanghai 9th People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China Background: Gypenosides (GPS) have been used as
Yang G, Wu F, Chen M, Jin J, Wang R, Yuan Y   +5 more
doaj  

Preparation, optimization, and characterization of genistein-ginseng long-acting polymeric gel as a breast cancer treatment alternative

Discover Oncology
To address the prevalent genistein (GST) metabolism and inadequate intestinal absorption, an oral long-acting and gastric in-situ gelling gel was designed to encapsulate and localize the intestinal release of the loaded genistein-ginseng (GST-GNS) solid ...
Samaa Abdullah, Shadab Md, Abeer A. Altamimi, Hadil Alahdal, Raisuddin Ali, Huda Mohammed Alkreathy, Shahid Karim   +6 more
doaj   +1 more source