Corticosterone mediates stress‐related increased intestinal permeability in a region‐specific manner [PDF]
, 2013 Background Chronic psychological stress (CPS) is associated with increased intestinal epithelial permeability and visceral hyperalgesia. It is unknown whether corticosterone (CORT) plays a role in mediating alterations of epithelial permeability in ...
Hong, S. +5 more
core +1 more source
International Journal of Nanomedicine, 2019 Gang Yang, Feihua Wu, Minyan Chen, Jian Jin, Rong Wang, Yongfang Yuan Department of Pharmacy, Shanghai 9th People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China Background: Gypenosides (GPS) have been used as
Yang G +5 more
doaj
Accelerated Reconstruction of Perfusion-Weighted MRI Enforcing Jointly Local and Nonlocal Spatio-temporal Constraints [PDF]
arXiv, 2017 Perfusion-weighted magnetic resonance imaging (MRI) is an imaging technique that allows one to measure tissue perfusion in an organ of interest through the injection of an intravascular paramagnetic contrast agent (CA). Due to a preference for high temporal and spatial resolution in many applications, this modality could significantly benefit from ...
arxiv
Asian Journal of Pharmaceutical Sciences, 2017 Oleanolic acid (OA) exhibited good pharmacological activities in the clinical treatment of hypoglycemia, immune regulation, acute jaundice and chronic toxic hepatitis.
Wenjuan Zhang +9 more
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Mechanisms and Modeling of the Intestinal Absorption, Activation, and Systemic Availability of Gemcitabine and a Gemcitabine Prodrug for Oral Administration [PDF]
, 2020 Gemcitabine (2’-2’-difluoro-deoxycytidine) is an intravenously administered nucleoside analogue used in the treatment of various solid tumor cancers.
Thompson, Brian
core
Journal of Traditional Chinese Medical Sciences, 2021 Objective: To determine the in vitro and in vivo absorption properties of active ingredients of the Chinese medicine, baicalein, to enrich mechanistic understanding of oral drug absorption.
Yang Liu +7 more
doaj
Development of an in Vitro Rat Intestine Segmental Perfusion Model to Investigate Permeability and Predict Oral Fraction Absorbed [PDF]
, 2018 Purpose: The aims of the study are to develop and evaluate an in vitro rat intestine segmental perfusion model for the prediction of the oral fraction absorbed of compounds and to assess the ability of the model to study intestinal metabolism.
Boursier-Neyret, Claire +8 more
core
Pharmaceutics, 2018 Raloxifene (RXF) is a hormone-like medication used for treating postmenopausal osteoporosis and estrogen-dependent breast cancer, yet associated with bad low bioavailability due to poor solubility. This study was intended to develop cyclodextrin/chitosan
Zaihua Wang, Yan Li
doaj +1 more source
Immediate expression of c-fos and c-jun mRNA in a model of intestinal autotransplantation and ischemia-reperfusion in situ [PDF]
, 2015 OBJECTIVE: Intestinal ischemia-reperfusion injury occurs in several clinical conditions and after intestinal transplantation. The aim of the present study was to investigate the phenomena of apoptosis and cell proliferation in a previously described ...
Coelho, Maria Cecilia Mendonça +6 more
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Health-promoting phenolic compounds in extra virgin olive oil: an integrated study of their concentration and bioavailability [PDF]
, 2021 [eng] The health promoting attributes associated with following a traditional Mediterranean diet have been reviewed extensively. The principal source of dietary fat in the Mediterranean diet is Extra virgin olive oil (EVOO) that contribute significantly ...
López Yerena, Anallely
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