Peanut skin polyphenols inhibit proliferation of leukemia cells in vitro, and its A-type procyanidins selectively pass through a Caco-2 intestinal barrier. [PDF]
Jantip PA+4 more
europepmc +1 more source
Systematic Study of Steroid Drugs' Ability to Cross Biomembranes-The Possible Environmental Impact and Health Risks Associated with Exposure During Pregnancy. [PDF]
Sobańska AW+6 more
europepmc +1 more source
Polymeric microcontainers improve oral bioavailability of a poorly soluble drug [PDF]
Boisen, Anja+5 more
core
Application of biomaterials in mesenchymal stem cell based endometrial reconstruction: current status and challenges. [PDF]
He L, Li Q.
europepmc +1 more source
Intestinal stem cells in intestinal homeostasis and colorectal tumorigenesis. [PDF]
Shi G, Li Y, Shen H, He Q, Zhu P.
europepmc +1 more source
Large-for-size syndrome prophylaxis in infant liver recipients with low body mass.
Semash K, Dzhanbekov T.
europepmc +1 more source
Intestinal Absorption by Perfusion in Situ
An apparatus and technique for the perfusion of a specific cannulated segment of small intestine of the rat, in situ, have been described. By the removal and analysis of perfusate samples from the system, continuous intestinal absorption curves have been established from a single animal in the steady state.
Francis A. Jacobs, Miltza Luper
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Intestinal Permeability of Forskolin byIn SituSingle Pass Perfusion in Rats
The intestinal permeability of forskolin was investigated using a single pass intestinal perfusion (SPIP) technique in rats. SPIP was performed in different intestinal segments (duodenum, jejunum, ileum, and colon) with three concentrations of forskolin (11.90, 29.75, and 59.90 µg/mL).
Zhenjun Liu+5 more
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The circadian timing system (CTS) governs the 24-h rhythm of the organism and, hence, also main pathways responsible for drug pharmacokinetics. P-glycoprotein (P-gp) is a drug transporter that plays a pivotal role in drug absorption, distribution, and elimination, and temporal changes in its activity may affect input, output, activity, and toxicity ...
Alper Okyar+5 more
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A simple, sensitive and specific reversed-phase high performance liquid chromatographic (RP-HPLC) assay for simultaneous determination of digoxin and permeability markers, in samples obtained from intestinal in situ single-pass perfusion studies, was developed and validated.
Manthena V. S. Varma+3 more
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