Results 191 to 200 of about 26,404 (336)

Endothelial Netrin‐4 regulates oligodendrocyte precursor cell proliferation and differentiation via ET‐1 signaling in preterm white matter injury

open access: yesBrain Pathology, EarlyView.
Our findings show early increased Netrin‐4 in mice with PWMI boosts angiogenesis and OPCs proliferation. Later, high levels hinder OPCs differentiation into mature cells, impairing myelination. It may act by stimulating ET‐1 secretion. Abstract Perinatal hypoxia–ischemia is a leading cause of preterm white matter injury (PWMI), yet mechanisms ...
Fuxing Dong   +8 more
wiley   +1 more source

A quad‐cistronic fluorescent biosensor system for real‐time detection of subcellular Ca2+ signals

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose The calcium ion (Ca2+) is a versatile cellular messenger regulating a variety of biological processes. Compounds modulating subcellular Ca2+ signals hold substantial pharmacological potential. Advances in fluorescent biosensors have revolutionised Ca2+ imaging.
Anna Lischnig   +7 more
wiley   +1 more source

Sensors Manufacturing on a 3D-Printed Transwell-Based Hybrid Organ-on-a-Chip for Non-Invasive Real-Time Biological Barrier Resistance Monitoring. [PDF]

open access: yesACS Biomater Sci Eng
Perottoni S   +8 more
europepmc   +1 more source

Tumors of the liver [PDF]

open access: yes, 1995
Iwatsuki, S, Starzl, TE
core  

Mitochondrial Ca2+ overload is a pivotal risk factor for lethal ventricular arrhythmias due to the oxidation of mitochondrial respirasome and energetic failure

open access: yesBritish Journal of Pharmacology, EarlyView.
The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez   +13 more
wiley   +1 more source

Emerging perspectives on leveraging physiologically based biopharmaceutics modeling (PBBM) for BCS class III biowaivers: A webinar summary. [PDF]

open access: yesJ Pharm Sci
Fang L   +8 more
europepmc   +1 more source

Multivisceral allotransplantation in pigs [PDF]

open access: yes, 1996
Furukawa, H   +4 more
core  

Influence of donor criteria on early outcome after intestinal transplantation [PDF]

open access: yes, 1997
Abu-Elmagd, K   +8 more
core   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade   +7 more
wiley   +1 more source

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