Results 41 to 50 of about 218,898 (267)

In situ stress distribution law of fault zone in tunnel site area based on the inversion method with optimized fitting conditions

open access: yesFrontiers in Earth Science, 2023
Tunnel construction in high geo-stress strata faces the risk of extreme natural disasters such as large squeezing deformation and rockburst. Therefore, it is of great significance to adopt a high-precision inversion method to investigate the distribution
Tiansheng Li   +4 more
doaj   +1 more source

In situ stress state in Mainland China [PDF]

open access: yespure and applied geophysics, 1995
In situ stress measurements are one of the important methods for studying the recent tectonic stress field and stress state. In this paper, the stress state and variation of stresses with depth in Mainland China are presented and analyzed on the basis of in situ stress data measured by both hydrofracturing and overcoring techniques.
openaire   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Influence of Stress Level on the Determination of In Situ Stress by DRA Method

open access: yesBuildings
Obtaining reliable in situ stress field data is the precondition of the design and excavation of underground engineering. The deformation rate analysis (DRA) method based on the rock deformation memory effect is an effective method for testing in situ ...
Yuxin Ban   +5 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

A Fiber Bragg Grating Borehole Deformation Sensor for Stress Measurement in Coal Mine Rock

open access: yesSensors, 2020
A borehole deformation sensor for long-term stress monitoring in coal mine rock based on optical fiber Bragg gratings (FBGs) is presented. The sensor converts borehole deformation into optical fiber strain by using four rings. For each ring, two FBGs are
Wusheng Zhao, Kun Zhong, Weizhong Chen
doaj   +1 more source

Experimental Study on the Effects of In Situ Stress on the Initiation and Propagation of Cracks during Hard Rock Blasting

open access: yesApplied Sciences, 2021
In situ stress is one of the most important factors affecting rock dynamic fractures during blasting excavation of deep rock mass that generally is hard rock.
Guangliang Yan   +5 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Prediction of fractures in tight carbonate gas reservoirs and analysis of main controlling factors: a case study on Dengying formation reservoir of Gaoshiti block in the Sichuan Basin

open access: yes矿业科学学报
Natural fractures are important storage spaces and seepage channels in tight carbonate reservoirs. It is therefore of practical significance to quantitatively predicting their development and distribution patterns and revealing the dominant geological ...
XU Ke
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

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