Results 131 to 140 of about 120,681,618 (266)

Molecular Identification of Human and Plant Pathogens in Municipal Domestic Wastewater for Hydroponic System Applications

International Journal of Microbiology
Water is essential for human survival and socioeconomic development, yet its overconsumption threatens global food security and ecosystem integrity. This necessitates a 60% increase in food production, further straining water resources.
Lukas Simon Kriem, Neil King, Sinja Niemann, Yevhen Vainshtein, Mirko Sonntag   +4 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

In-vitro testing of plasma sprayed hydroxyapatire coatings

in-vitro, hydroxyapatite ...
Gross, Kārlis-Agris, Berndt, CC
core  

Efeitos estruturais do cultivo in vitro e aclimatização ex vitro em raiz e folha de espécies de Cattleya Lindl. (Orchidaceae) [PDF]

, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Programa de Pós-Graduação em Recursos Genéticos Vegetais, Florianópolis, 2015.A propagação in vitro de orquídeas constitui um dos métodos mais conhecidos e ...
Lando, Ana Paula
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

In vitro polyketide biocatalysis : triketide building-blocks and enzymology [PDF]

, 2013
textPolyketide products are useful compounds to research and industry but can be difficult to access due to their richness in stereogenic centers. Type I polyketide synthases offer unique engineering opportunities to access natural stereocontrol and ...
Harper, Andrew David
core  

Comparação entre vitrificação e congelamento lento sobre o desenvolvimento pós-descongelamento de embriões bovinos produzidos in vitro

Semina: Ciências Agrárias
Avaliou-se o desenvolvimento pós-descongelamento de embriões bovinos produzidos in vitro (PIV) criopreservados pela técnica de vitrificação e de congelamento lento em diferentes dias após a fertilização in vitro (FIV). Foram realizadas 9 réplicas de PIV.
Vanessa Rachele Ribeiro Nunes, Jennifer Teodoro Ferreira Gregianini, Helton Aparecido Garcia Gregianini, Bárbara Souza Fantin, Bárbara Loureiro, Rafael Augusto Satrapa   +5 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

In vitro neurotoxicology: an introduction

, 2011
This introductory Chapter provides a brief overview of the field of neurotoxicology and of the role played by in vitro approaches in investigations on mechanisms of neurotoxicity and of developmental neurotoxicity, and in providing suitable models for ...
GUIZZETTI M., GIORDANO G., COSTA, Lucio Guido, Marina Guizzetti, Lucio G. Costa, Gennaro Giordano   +5 more
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source