Results 141 to 150 of about 8,610,712 (380)

Perbanyakan Dan Konservasi in Vitro Plasma Nutfah Talas (Colocasia Esculenta (L.) Schoot) [PDF]

, 2012
Taro is a potential source of carbohydratefor anticipation of climate change. In vitro technology havenot been widely implemented for tuber crops conservation.Conservation of the crops is mostly conducted in field. Suchconservation is very susceptible to
Dewi, I. S. (Iswari), Dewi, N. (Nurwita), Hanarida, I. (Ida), Purwito, A. (Agus), Purwoko, B. S. (Bambang)   +4 more
core  

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

CULTIVATION IN VITRO OF MALIGNANT TUMORS [PDF]

, 1911
Alexis Carrel, Montrose T. Burrows
openalex   +1 more source

Teknik Pengujian in Vitro Ketahanan Pisang Terhadap Penyakit Layu Fusarium Menggunakan Filtrat Toksin Dari Kultur Fusarium Oxysporum F. SP. Cubense [PDF]

, 2005
Sejauh ini informasi mengenai uji ketahanan pisang terhadap patogen layu fusarium menggunakan filtrat toksin patogennya masih terbatas. Penelitian ini dilaksanakan pada bulan Juni 2002 sampai dengan Maret 2003 di laboratorium kultur jaringan ...
Handayani, H. (H), Jumjunidang, J. (Jumjunidang), Nasir, N. (Nasril), Riska, R. (Riska)   +3 more
core  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro

Antiviral Research, 2020
L. Caly, J. Druce, M. Catton, D. Jans, K. Wagstaff   +4 more
semanticscholar   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Flow cytometric quantification of neutral lipids in a human skin stem cell-derived model of NASH

MethodsX, 2020
Non-alcoholic steatohepatitis (NASH) is a severe chronic liver disease that affects 3 to 5 percent of the world population. It is characterized by hepatic lipid accumulation and inflammation and can progress towards fibrosis, cirrhosis and hepatocellular
Joost Boeckmans, Alessandra Natale, Matthias Rombaut, Karolien Buyl, Tamara Vanhaecke, Vera Rogiers, Robim M Rodrigues, Joery De Kock   +7 more
doaj  

THE IN VITRO AND IN VIVO EFFECT OF SULFONAMIDES UPON THE STREPTOCOCCAL ANTIFIBRINOLYSIN TEST [PDF]

, 1942
William Kirby, Lowell A. Rantz
openalex   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source