Results 201 to 210 of about 5,914,882 (359)

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Physiologically-Based Pharmacokinetic Modeling of the PARP Inhibitor Niraparib. [PDF]

open access: yesCPT Pharmacometrics Syst Pharmacol
Lewis GJ   +3 more
europepmc   +1 more source

A Ca2+/CaM‐dependent kinase from pea is stress regulated andin vitrophosphorylates a protein that binds toAtCaM5promoter [PDF]

open access: bronze, 2002
Sona Pandey   +5 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Composição química e digestibilidade 'in vitro' de silagens de milho com distintos teores de umidade e níveis de compactação [PDF]

open access: gold, 2005
Clóvis Clenio Diesel Senger   +4 more
openalex   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Modulatory effects of CeO<sub>2</sub> nanoparticles on bleomycin-induced active pulmonary disease processes in animal and human airway epithelium models. [PDF]

open access: yesPart Fibre Toxicol
Guo C   +8 more
europepmc   +1 more source

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