Results 111 to 120 of about 165,330 (303)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Morfo-histodiferenciação de estruturas semelhantes a protocormos de Cattleya Tigrina A. Rich (Orchidaceae) cultivadas in vitro através da técnica de camada fina celular [PDF]

open access: yes, 2013
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.Cattleya tigrina é orquídea epífita de grande valor econômico ornamental que, todavia, encontra-se ameaçada.
Pereira-Dias, Francis Pereira-Dias
core  

Enhancing felid conservation: Exploring the impact of in vitroculture media on domestic cat blastocyst production [PDF]

open access: yes
This study investigated the optimization of assisted reproductive techniques for wild felid conservation, focusing on in vitro procedures using the domestic cat as a model species.
Sánchez Calabuig, María Jesús   +14 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Approaches for in vitro conservation of woody plants germplasm [PDF]

open access: yes, 2015
The conservation of plant genetic diversity aims at preserving as much as possible extant species by using innovative and complementary approaches to guarantee the effectiveness of the safeguarding strategies and to face present problems and future ...
Dolce, Natalia Raquel   +4 more
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

In vitro conservation of sugarcane germplasm [PDF]

open access: yes, 2002
O objetivo deste trabalho foi avaliar o efeito da temperatura, de sacarose, manitol e sorbitol, como fontes de carbono e reguladores osmóticos, e do ácido abscísico, como regulador de crescimento na conservação in vitro de germoplasma de cana-de-açúcar ...
Lemos, Eurico Eduardo Pinto de   +4 more
core  

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Genetic load and viability of a future restored northern white rhino population

open access: yesEvolutionary Applications
As biodiversity loss outpaces recovery, conservationists are increasingly turning to novel tools for preventing extinction, including cloning and in vitro gametogenesis of biobanked cells.
Aryn P. Wilder   +6 more
doaj   +1 more source

In Vitro Regeneration, Micropropagation and Germplasm Conservation of Horticultural Plants [PDF]

open access: yes
Plant tissue culture is an important and continually emerging field applied to improve the production, propagation, and conservation of cultivated and wild plant species.

core   +1 more source

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