Establishment of Efficient In vitro Culture Protocol and Screening of Soma clonal Variation Among Regenerated Plants in Cumin (Cuminum cyminum L.) [PDF]
, 2022 Nashwa A. Hussien +4 more
openalex +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Control of contaminants in the in vitro establishment of Guadua latifolia
Pesquisa Agropecuária Tropical, 2020 The Amazonian bamboo forests are located in an important region of high biodiversity in Brazil, Peru and Bolivia, forming the largest native bamboo forest reserve in the world.
João Ricardo Avelino Leão +3 more
doaj +1 more source
SARS CoV subunit vaccine: Antibodymediated neutralisation and enhancement [PDF]
, 2012 1. A SARS vaccine was produced based on recombinant native full-length Spike-protein trimers (triSpike) and efficient establishment of a vaccination procedure in rodents. 2.
Altmeyer, R +14 more
core +1 more source
A systematic review of platinum and taxane resistance from bench to clinic: an inverse relationship [PDF]
, 2007 We undertook a systematic review of the pre-clinical and clinical literature for studies investigating the relationship between platinum and taxane resistance.
Davey, Ross +2 more
core +1 more source
Model experiments for establishment of in vitro culture by micrografting in apple
International Journal of Horticultural Science, 2005 Micrografting was used in our experiments for establishment of in vitro culture from one rootstock (`JTE-F') and three scion cultivars (`Remo', 'Rewena' and `Reanda') of apple.
J. Dobránszky +3 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Establishment of in vitro Src tyrosine kinase inhibitors screening model
浙江大学学报. 农业与生命科学版, 2007 A model system for rapid screening of Src tyrosine kinase inhibitors was established in vitro, and it is the foundation of screening tyrosine kinase activity inhibitors.
WANG Chen-hui, SHI Ying, GONG Xing-guo
doaj +1 more source
Innovative in vitro methodologies for establishing therapeutic equivalence.
Revista panamericana de salud publica = Pan American journal of public health, 2018 To improve the quality of pharmaceutical products in their markets, several Latin American countries have begun to require that new generic products demonstrate bioequivalence against innovator or reference products. However, given the number of products involved, it is not feasible to rely on clinical studies to comply with this requirement.
Lisa Murray +4 more
openaire +2 more sources