Results 171 to 180 of about 670,418 (378)

Optimumin vitroexpansion of human antigen-specific CD8+ T cells for adoptive transfer therapy [PDF]

, 2005
Monica Montes, Nathalie Rufer, Victor Appay, Stéphanie Reynard, M. J. Pittet, Daniel E. Speiser, Philippe Guillaume, J C Cerottini, Pedro Romero, Serge Leyvraz   +9 more
openalex   +1 more source

Computational design of artificial organs [PDF]

, 2008
C
De Beule, Matthieu, Verdonck, Pascal
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

The antimicrobial peptide TAT-RasGAP317-326 inhibits the formation and expansion of bacterial biofilms in vitro

, 2021
Tytti Heinonen, Simone Hargraves, Maria Georgieva, Christian Widmann, Nicolas Jacquier   +4 more
openalex   +1 more source

Mesenchymal stem cells and their use as cell replacement therapy and disease modelling tool. [PDF]

, 2008
Mesenchymal stem cells (MSCs) from adult somatic tissues may differentiate in vitro and in vivo into multiple mesodermal tissues including bone, cartilage, adipose tissue, tendon, ligament or even muscle. MSCs preferentially home to damaged tissues where
García-Castro, J, Madrenas, J, Menendez, P, Pérez-Simón, JA, Rodriguez, R, Trigueros, C   +5 more
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Decreased CRISPLD2 expression impairs osteogenic differentiation of human mesenchymal stem cells during in vitro expansion. [PDF]

J Cell Physiol, 2023
Rong W, Rome CP, Dietrich MA, Yao S.
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Quantifying epistatic interactions among the components constituting the protein translation system

Molecular Systems Biology, 2009
In principle, the accumulation of knowledge regarding the molecular basis of biological systems should allow the development of large‐scale kinetic models of their functions.
Tomoaki Matsuura, Yasuaki Kazuta, Takuyo Aita, Jiro Adachi, Tetsuya Yomo   +4 more
doaj   +1 more source

Bovine Fibroblast-Derived Extracellular Matrix Promotes the Growth and Preserves the Stemness of Bovine Stromal Cells during In Vitro Expansion. [PDF]

J Funct Biomater, 2023
Lee K, Jackson A, John N, Zhang R, Ozhava D, Bhatia M, Mao Y.   +6 more
europepmc   +1 more source