Results 341 to 350 of about 670,418 (378)

In Vitro Expansion of Hematopoietic Cells for Clinical Application

1995
The past 15 years have seen a tremendous explosion in our knowledge of the molecular and cellular regulation of hematopoietic differentiation. Launched with the identification and purification of candidate hematopoietic stem cells by Visser et al. in 1984 [1] and the molecular cloning of recombinant human (rH-) granulocyte macrophage-colony stimulating
Stephen G. Emerson, Bernhard O. Palsson, Michael F. Clarke, Samuel M. Silver, Paul T. Adams, Manfred R. Koller, Gary Van Zant, Susan Rummel, R. Douglas Armstrong, James Maluta, Judith Douville, Leslie Paul   +11 more
openaire   +2 more sources

In Vitro Expansion and Transplantation of Intestinal Crypt Stem Cells

Gastroenterology, 2012
Adult tissue stem cells hold great promise for regenerative medicine strategies. Major hurdles in their clinical application persist and include the identification of such stem cells, their isolation and in vitro expansion, and—finally—their transplantation. These hurdles have recently been overcome for stem cells of the intestinal tract.
Li, V.S., Clevers, H.
openaire   +3 more sources

Mesenchymal Stem Cells: Isolation, In Vitro Expansion and Characterization

2006
Mesenchymal stem cells (MSC), one type of adult stem cell, are easy to isolate, culture, and manipulate in ex vivo culture. These cells have great plasticity and the potential for therapeutic applications, but their properties are poorly understood. MSCs can be found in bone marrow and in many other tissues, and these cells are generally identified ...
N, Beyer Nardi, L, da Silva Meirelles
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In Vitro Expansion of Tissue Cells by Conditional Proliferation

2007
Cell therapies rely on the implantation of well-characterized functional cells with defined properties. Often, the cells of interest do not proliferate in vitro and thus cannot be expanded to the amount needed for characterization, purification, manipulation, or cloning.
Tobias, May, Hansjörg, Hauser, Dagmar, Wirth   +2 more
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In Vitro Erythroid Cell Expansion Analysis in Polycythemia Vera.

Blood, 2006
Abstract Polycythemia vera (PV) is an acquired myeloproliferative clonal stem cell disorder characterized by cytokine hypersensitivity. The erythroid colony forming assay has been useful in PV diagnosis. However, studies aiming to elucidate molecular mechanism in PV pathogenesis often require large numbers of cells from a specific ...
Jaroslav F. Prchal, Josef T. Prchal, Archana M. Agarwal, Hana Bruchova, Donghoon Yoon   +4 more
openaire   +1 more source

Methodology for Optimal In Vitro Cell Expansion in Tissue Engineering

2008
Expansion of the cell population in vitro has become an essential step in the process of tissue engineering and also the systematic optimization of culture conditions is now a fundamental problem that needs to be addressed. Herein, we provide a rational methodology for searching culture conditions that optimize the acquisition of large quantities of ...
J M, Melero-Martin, S, Santhalingam, M, Al-Rubeai   +2 more
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Clonal expansion of IgM B memory cells in vitro

Cellular Immunology, 1978
Abstract Clonal development of Srbc-primed IgM B cell precursors has been studied in vitro . Cells were cultured in the presence of LPS and Srbc, as well as additional T cells derived from three sources: specific Srbc-activated T cells, allogeneic spleen cells and normal thymus cells.
openaire   +2 more sources

Biomechanical properties of skin in vitro for different expansion methods

Clinical Biomechanics, 2004
In plastic surgery, clinicians are interested in replacing conventional expansion by rapid expansion, because the expansion period could be shortened greatly. Also people are concerned that skin properties after rapid expansion might not approach those after conventional expansion.Biomechanical testing of skin for different expansion methods.It would ...
Yan-Jun, Zeng, Yu-Hong, Liu, Chuan-Qing, Xu, Xiao-Hu, Xu, Hong, Xu, Guang-Ci, Sun   +5 more
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Numerical Methods for the Design and Description of In Vitro Expansion Processes of Human Mesenchymal Stem Cells.

Advances in Biochemical Engineering/Biotechnology, 2020
Valentin Jossen, D. Eibl, R. Eibl
semanticscholar   +1 more source

In Vitro Expansion of Megakaryocytes from Peripheral Blood Hematopoietic Progenitors

2003
Recently, there have been several reports describing the in vitro proliferation and differentiation of megakaryocytic progenitor cells, isolated from either bone marrow (BM) or peripheral blood (PB), into relatively pure human mega-karyocytes (1,2).
M A, Thornton, M, Poncz
openaire   +2 more sources