Results 201 to 210 of about 805,984 (229)
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Pseudomonas aeruginosa Recombinant L-asparaginase: PEGylation with Low Molecular Weight Polyethylene Glycol, Molecular Dynamics Simulation, In vitro and In vivo Serum half-life and Biochemical Characterization

Current Pharmaceutical Biotechnology
Background: Microbial L-asparaginase (L-ASNase, EC 3.5.1.1) is a pivotal biopharmaceutical drug-protein that catalyzes the hydrolysis of the non-essential amino acid L-asparagine (L-Asn) into L-aspartic acid (L-Asp) and ammonia , resulting in deplenishing the cellular L-Asn pool, which leads to the ultimate death of the L-asparagine synthetase (L-ASNS)
Rawan, Alshamy   +5 more
openaire   +2 more sources

Impact of Encapsulation on in vitro and in vivo Performance of Volatile Nanoscale Phase-Shift Perfluorocarbon Droplets.

Ultrasound in Medicine and Biology, 2018
Phase-shift droplets can be converted by sound from low-echogenicity, liquid-core agents into highly echogenic microbubbles. Many proposed applications in imaging and therapy take advantage of the high spatiotemporal control over this dynamic transition.
Kimoon Yoo   +5 more
semanticscholar   +1 more source

Effect of whole-body irradiation on the half-life of antipyrine and on the microsomal enzyme system of rats. Correlation between in vivo and in vitro results.

Enzyme, 1983
An increase in half-life of antipyrine and a decrease in the metabolic capacity of microsomes were observed in rats 4 and 6 days after the in vivo gamma-irradiation. A correlation was noted between the in vivo half-life of antipyrine and the in vitro microsomal data.
C, Thiriot, F, Gaboriaud, P, Bernard
openaire   +1 more source

SARS-CoV-2 variant evasion of monoclonal antibodies based on in vitro studies

Nature Reviews Microbiology, 2022
, William T Harvey, Joseph Hughes
exaly  

Antiviral neutralizing antibodies: from in vitro to in vivo activity

Nature Reviews Immunology, 2023
Dennis R Burton
exaly  

In vitro selection of aptamers and their applications

Nature Reviews Methods Primers, 2023
, Erin M Mcconnell, Maureen McKeague
exaly  

Fusion of an albumin-binding domain extends the half-life of immunotoxins.

International journal of pharmaceutics, 2016
Rui Guo   +8 more
semanticscholar   +1 more source

[Half-life of mRNA synthesized in vitro in mitochondria of animal cells].

Bollettino della Societa italiana di biologia sperimentale, 1974
M N, Gadaleta, C, Saccone
openaire   +1 more source

U1 snRNP regulates cancer cell migration and invasion in vitro

Nature Communications, 2020
Jung-Min Oh, Chao Di, Anna Maria Pinto
exaly  

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