Results 211 to 220 of about 114,426,039 (308)

Sericin Supplementation Prior to and During In Vitro Maturation Mitigates H₂O₂-Induced Oxidative Stress in Bovine Oocytes. [PDF]

Vet Med Int
Yindeetrakul S, Triwutanon S, Sangmalee A, Rukkwamsuk T.   +3 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Chemically defined 3D matrix for in vitro maturation (IVM) of human oocytes. [PDF]

JBRA Assist Reprod
Bos-Mikich A, Andrade GM, Santos LALD, Frantz N.   +3 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Ovarian tissue oocyte-in vitro maturation combined with ovarian tissue cryopreservation: a promising urgent fertility preservation strategy for hematological patients before HSCT. [PDF]

J Ovarian Res
Ding Y, Su T, Wan Y, Hou Y, Fan Y, Fang F, Zuo P, Li X, Duan S, Huang N, Wang J, Xu L, Liang R, Tian L.   +13 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Rates and risk factors of oocyte immaturity: toward personalized selection for rescue in vitro maturation. [PDF]

J Assist Reprod Genet
Taggi M, Maggiulli R, Innocenti F, Casciani V, Cermisoni GC, Soscia DM, Petrone P, Ruffa A, Albricci L, Fiorentino G, Zuccotti M, Vaiarelli A, Capalbo A, Coticchio G, Rienzi L, Cimadomo D.   +15 more
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Advances in human oocyte in vitro maturation: current status and future perspectives: a narrative review. [PDF]

Reprod Fertil
Liu M, Cui J, Chang HM, Liu J, Leung PCK.   +4 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source