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In Vitro Techniques and Measurements of Phage Characteristics That Are Important for Phage Therapy Success. [PDF]
Validated methods for phage selection, host range expansion, and lytic activity determination are indispensable for maximizing phage therapy outcomes. In this review, we describe some relevant methods, highlighting their advantages and disadvantages, and
Glonti T, Pirnay JP.
europepmc +2 more sources
Useful In Vitro Techniques to Evaluate the Mucoadhesive Properties of Hyaluronic Acid-Based Ocular Delivery Systems. [PDF]
Polymer-based eye drops are the most used drug delivery system to treat dry eye disease (DED). Therefore, the mucoadhesion between the polymer and the ocular mucin is crucial to ensure the efficacy of the treatment.
Graça A+4 more
europepmc +2 more sources
Techniques for the Assessment of In Vitro and In Vivo Antifungal Combinations [PDF]
Systemic fungal infections are associated with high mortality rates despite adequate treatment. Moreover, acquired resistance to antifungals is increasing, which further complicates the therapeutic management. One strategy to overcome antifungal resistance is to use antifungal combinations.
Patrick Schwarz+4 more
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In vitro techniques to assess the proficiency of skin care cosmetic formulations. [PDF]
Cosmetics comprising either natural or synthetic components are used almost regularly and universally in different forms to enhance the beauty. The utmost disclosure of human membrane to sunlight and environmental pollution results in the exhibition of ...
Roy A+5 more
europepmc +2 more sources
Effectiveness of in vitro maturation and in vitro fertilization techniques in pigs [PDF]
In vitro maturation and in vitro fertilization techniques in pigs have progressed considerably in recent years. Many reports focus on the factors affecting in vitro maturation that lead to normal male pronuclear formation or monospermy after fertilization in vitro.
K. Niwa
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In Vitro Techniques for the Assessment of Neurotoxicity
Risk assessment is a process often divided into the following steps: a) hazard identification, b) dose-response assessment, c) exposure assessment, and d) risk characterization. Regulatory toxicity studies usually are aimed at providing data for the first two steps.
G. J. Harry+9 more
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Chickpea Hybridization Using In Vitro Techniques [PDF]
Tissue culture techniques play an important role in the utilization of wild Cicer species for the improvement- of cultivated chickpea. Utilization of wild Cicer species has become essential as a series of evolutionary bottlenecks have narrowed the genetic base of chickpea, thus making it susceptible to a range of diseases and pests.
Mallikarjuna, N, Muehlbauer, F J
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A number of studies by the author and other investigators are reviewed in which the in vitro kidney slice technique has been used to evaluate the nephrotoxicity of various compounds. The kidney slice technique can be used to determine the effect of prior
G. H. Hirsch
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In Vitro techniques for studying drug metabolism [PDF]
A considerable amount of information has been obtained about human enzymes involved in drug metabolism. Cytochrome P450 is presented as a paradigm in order to illustrate the experimental techniques now available. In vitro assays can be done with tissue slices, microsomes, or even short-term cell cultures.
F. Guengerich
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In Vitro Techniques for ADP-Ribosylated Substrate Identification
ADP-ribosylation is a post-translational modification of proteins that has required the development of specific technical approaches for the full definition of its physiological roles and regulation. The identification of the enzymes and specific substrates of this reaction is an instrumental step toward these aims.
Grimaldi Giovanna+3 more
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