Results 1 to 10 of about 1,231,600 (254)

Modern In Vitro Techniques for Modeling Hearing Loss. [PDF]

open access: yesBioengineering (Basel)
Sensorineural hearing loss (SNHL) is a prevalent and growing global health concern, especially within operational medicine, with limited therapeutic options available. This review article explores the emerging field of in vitro otic organoids as a promising platform for modeling hearing loss and developing novel therapeutic strategies.
Shah JJ   +4 more
europepmc   +4 more sources

In vivo and in vitro random mutagenesis techniques in plants [PDF]

open access: yesEFSA Journal, 2021
Mutations are changes in the genetic material that may be transmitted to subsequent generations. Mutations appear spontaneously in nature and are one of the underlying driving forces of evolution. In plants, in vivo and in vitro random mutagenesis relies on the application of physical and chemical mutagens to increase the frequency of mutations thus ...
EFSA Panel on Genetically Modified Organisms (GMO)   +20 more
openaire   +8 more sources

Assessment of the Diagnostic Ability of Four Detection Methods Using Three Sample Types of COVID-19 Patients

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
BackgroundViral nucleic acid detection is considered the gold standard for the diagnosis of coronavirus disease 2019 (COVID-19), which is caused by SARS-CoV-2 infection.
Fei Yu   +42 more
doaj   +1 more source

Differential proteomic analysis of plasma-derived exosomes as diagnostic biomarkers for chronic HBV-related liver disease

open access: yesScientific Reports, 2022
Hepatitis B virus (HBV) infection is still a major public health problem worldwide. We aimed to identify new, non-invasive biomarkers for the early diagnosis of chronic HBV-related diseases, reveal alterations in the progression of chronic hepatitis B ...
Bo Ye   +6 more
doaj   +1 more source

Molecular Portrait of GISTs Associated With Clinicopathological Features: A Retrospective Study With Molecular Analysis by a Custom 9-Gene Targeted Next-Generation Sequencing Panel

open access: yesFrontiers in Genetics, 2022
Objectives: The study aims to investigate genetic characterization of molecular targets and clinicopathological features with gastrointestinal stromal tumors based on targeted next-generation sequencing.Materials and Methods: We selected 106 patients ...
Haoran Qian   +8 more
doaj   +1 more source

ddPCR provides a sensitive test compared with GeneXpert MTB/RIF and mNGS for suspected Mycobacterium tuberculosis infection

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
IntroductionThe Metagenomics next-generation sequencing (mNGS) and GeneXpert MTB/RIF assay (Xpert) exhibited a sensitivity for tuberculosis (TB) diagnostic performance. Research that directly compared the clinical performance of ddPCR analysis, mNGS, and
Dan Zhang   +24 more
doaj   +1 more source

Evaluation of multiplex ARMS-PCR for detection of Helicobacter pylori mutations conferring resistance to clarithromycin and levofloxacin

open access: yesGut Pathogens, 2020
Background Helicobacter pylori bacterium is a major cause of gastritis. With increasing use of antibiotics to treat infections, mutation resistant strains have emerged in most human populations.
Yangxia Li   +7 more
doaj   +1 more source

A simple method for the construction of electrode arrays [PDF]

open access: yes, 1984
A simple method is described for the construction of electrode arrays consisting of insulated metal wires (33 μm diameter) spaced at small, equal distances (0.1 mm).
Holsheimer, J., Verloop, A.J.
core   +9 more sources

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