Effect of hydroalcoholic extracts of flower and fruit peel of Punica granatum on Leishmania major promastigotes in vitro [PDF]
Background and aims: Cutaneous leishmaniasis is one of the endemic parasitic diseases in many regions of Iran for which there is currently no complete vaccine and effective drugs without drug resistance to prevent and treat it.
Hamidreza Mardani +5 more
doaj
Tissue culture of oil palm : finding the balance between mass propagation and somaclonal variation [PDF]
The oil palm (Elaeis guineensis Jacq.) is typically propagated in vitro by indirect somatic embryogenesis, a process in which somatic cells of an explant of choice are, via an intermediate phase of callus growth, induced to differentiate into somatic ...
Inzé, Dirk, Maene, Ludo, Weckx, Sylvie
core +2 more sources
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Is Novamin Toothpaste Effective on Enamel Remineralization? An In-Vitro Study
Objectives: New bio-active glass containing toothpaste (NovaMin) is one of the most effective cariostatic products when used as a daily application the aim of this in-vitro study is to evaluate the influence of NovaMin on enamel remineralization ...
Damla Aksit Bıçak +4 more
doaj +1 more source
Hydrogen peroxide in micropropagation of Lilium: A comparison with a traditional methodology [PDF]
The micropropagation of Lilium longiflorum requires adequate equipment which may not be afforded by small laboratories or producers. In this work we compared traditional methodology with a protocol that included easily available elements to sterilize ...
Curvetto, Nestor Raul +2 more
core
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Antimicrobial Action of Compounds from Marine Seaweed
Seaweed produces metabolites aiding in the protection against different environmental stresses. These compounds show antiviral, antiprotozoal, antifungal, and antibacterial properties.
María José Pérez +2 more
doaj +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
The effect of leukaemia inhibitory factor (LIF) on bovine embryo development in vitro : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science in Animal Science at Massey University [PDF]
The aim of the study was to investigate the effect of Leukaemia Inhibitory Factor (LIF) either during in vitro maturation (IVM) or in vitro culture (IVC) on bovine embryo development. Three main experiments were conducted using oocytes aspirated from 2-8
Margawati, Endang Tri
core

