Results 111 to 120 of about 3,163,170 (322)

Alternative method for the evaluation of monovalent inactivated foot and mouth disease virus vaccine

open access: yesVacciMonitor, 2021
Foot and mouth disease is a highly contagious viral disease of cloven-hoofed animals that has a significant economic impact on livestock. A recent outbreak was detected and recorded as exotic strain of foot and mouth disease virus SAT2 (Serotype SAT2 ...
M.S. Abousenna   +5 more
doaj  

Tryptophan‐sensing receptor GPR142 expression levels are directly regulated by proinflammatory cytokines in ghrelin‐producing cells

open access: yesFEBS Open Bio, EarlyView.
GPR142, a tryptophan‐sensing receptor, stimulates gastrointestinal hormones like ghrelin and is linked to inflammation regulation. Proinflammatory cytokines suppress ghrelin production, while tryptophan levels decrease via IDO1 activation. Our findings reveal that proinflammatory cytokines directly regulate GPR142 expression in ghrelin‐producing cells,
Yoko Ueda   +15 more
wiley   +1 more source

Evaluation of antitrichomonal effect of methanolic extract of Hyssopus officinalis on Trichomonas vaginalis in vitro

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2021
Background and Objectives: Trichomonas vaginalis is a flagellate protozoan that is the most common sexually parasitic transmitted infection in the world. Metronidazole is currently used for the treatment of trichomoniasis, which has side effects.
Roghayeh Norouzi   +5 more
doaj  

Antimicrobial Action of Compounds from Marine Seaweed

open access: yesMarine Drugs, 2016
Seaweed produces metabolites aiding in the protection against different environmental stresses. These compounds show antiviral, antiprotozoal, antifungal, and antibacterial properties.
María José Pérez   +2 more
doaj   +1 more source

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

open access: yesFEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law   +6 more
wiley   +1 more source

Piezo1 channels enhance anabolic signaling activation induced by electrical stimulation of cultured myotubes

open access: yesFEBS Open Bio, EarlyView.
By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya   +3 more
wiley   +1 more source

Role of connectivity anisotropies in the dynamics of cultured neuronal networks [PDF]

open access: yesarXiv
Laboratory-grown, engineered living neuronal networks in vitro have emerged in the last years as an experimental technique to understand the collective behavior of neuronal assemblies in relation to their underlying connectivity. An inherent obstacle in the design of such engineered systems is the difficulty to predict the dynamic repertoire of the ...
arxiv  

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