Results 261 to 270 of about 1,276,228 (308)
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In vitro techniques to evaluate buccal films
Journal of Controlled Release, 2013Extensive research on transmucosal drug delivery in the past few decades has resulted in the clinical application of several drug molecules through the buccal route. Interestingly, most of the new chemical moieties under clinical trials are being screened for their potential to deliver through the buccal cavity.
Anroop B, Nair +5 more
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In Vitro Clotting Technique for Hemodialysis Circuits
ASAIO Journal, 1999Physiologic clotting of a dialysis circuit was achieved using an in vitro method. The closed loop method used a circuit filled with defibrinated bovine blood. To achieve clotting, a slow infusion (5-15 ml/hr) of ACD bovine plasma was performed. The rate and amount of infusion of the plasma allowed for careful control of the amount of clotting in the ...
James A. Summerton +2 more
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In vitro techniques in fox reproduction
Livestock Production Science, 1993Abstract The domestic blue fox ( Alopex lagopus ) is extensively farmed in Scandinavia, and represents a genetic reserve, as well as a model for basic reproductive studies for the wild arctic fox, which is a canid species threatened by extinction.
W. Farstad +4 more
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Sonographic techniques in human in-vitro fertilization programmes
Human Reproduction, 1988The value of ultrasound in programmes of in-vitro fertilization is discussed. In order to reach the ovaries, the transvesical route was first introduced, and proved less invasive than laparoscopy. The periurethral route has also been used. The transvaginal approach, especially using a vaginal transducer with an attached needle guide, has attracted many
M, Wikland +3 more
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In vitro skin permeation techniques
Journal of Controlled Release, 1992Abstract This paper reviews various techniques used to assess permeation of drugs into and through skin under in vitro conditions. There have been a wide variety of diffusion cells designed for in vitro measurement of skin permeation. These cells have generally been designed in one of two ways: side-by-side (bichambers) and vertical in vivo mimic ...
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In Vivo and In Vitro Starch Digestion: Are Current in Vitro Techniques Adequate?
Biomacromolecules, 2010The time evolution of the size distributions of (fully branched and debranched) starch molecules during in vivo and in vitro digestion was analyzed using size exclusion chromatography (SEC) and compared. In vivo digesta were collected from the small intestine of pigs fed with raw normal maize starch; in vitro digestion was carried out on the same diet ...
Hasjim, Jovin +3 more
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In Vitro techniques for studying drug metabolism
Journal of Pharmacokinetics and Biopharmaceutics, 1996A considerable amount of information has been obtained about human enzymes involved in drug metabolism. Cytochrome P450 is presented as a paradigm in order to illustrate the experimental techniques now available. In vitro assays can be done with tissue slices, microsomes, or even short-term cell cultures.
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1984
The control of malaria by chemotherapy, the use of pesticides, and public health measures has been curtailed by the increasing spread of drug resistance of the parasite, especially Plasmodium falciparum, while increased tolerance of the mosquito vectors to the older insecticides has exacerbated the global malaria problem by facilitating the return of ...
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The control of malaria by chemotherapy, the use of pesticides, and public health measures has been curtailed by the increasing spread of drug resistance of the parasite, especially Plasmodium falciparum, while increased tolerance of the mosquito vectors to the older insecticides has exacerbated the global malaria problem by facilitating the return of ...
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In Vitro Micronucleus Technique to Predict Chemosensitivity
2005The study of DNA damage at the chromosome level is an essential part of genetic toxicology because chromosomal mutation is an important event in carcinogenesis. The micronucleus assays have emerged as one of the preferred methods for assessing chromosome damage because they enable both chromosome loss and chromosome breakage to be measured reliably ...
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Cellular and In Vitro Techniques
1986This chapter will consider the attempts that have been made to date to make use of cells in culture to measure toxicity. The past decade has seen some major advances in biotechnology. For some years now it has been possible to isolate individual mammalian genes and to transfer these into bacteria, or indeed to other mammalian cells. By the construction
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