Results 271 to 280 of about 1,429,532 (349)

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Demonstrating the Absence of Correlation Between Molecular Docking and in vitro Cytotoxicity in Anti-Breast Cancer Research: Root Causes and Practical Resolutions. [PDF]

Breast Cancer (Dove Med Press)
Megantara S, Rusdin A, Budiman A, Puluhulawa LE, Ikram NKBK, Muchtaridi M.   +5 more
europepmc   +1 more source

Overcoming Recurrent Pregnancy Loss with Advanced Fertility Techniques: A Case Report on Combined Stem Cell Therapy, In-vitro Activation and Lymphocyte immunotherapy [PDF]

Niket Patel, Nayana Patel, Molina Patel, Harsha K Bhadarka, Paresh Ghoghari, Sachin Dhaduk, Piyush Chudasama, Kairavi Vyas   +7 more
openalex   +1 more source

Oligohistidine‐Functionalized Single‐Walled Carbon Nanotube‐Guided RNA Delivery to Improve Shoot Regeneration Efficiency in Plant Calli

Advanced Functional Materials, EarlyView.
The pH‐sensitive His6‐SWNTs, which is functionalized with oligohistidine, can deliver STTM396 molecules into callus cells. The STTM396–SWNT complex treatments enhance shoot regeneration efficiency by regulating the miR396‐GRF module in Arabidopsis and tomato calli.
Yeong Yeop Jeong, Hyuna Kwak, Woojin Jeong, Hongwoo Lee, Su‐Ji Jeon, Hyo‐Jun Lee, Pil Joon Seo, Seon‐Yeong Kwak   +7 more
wiley   +1 more source

Editorial: Integrating computational modeling and organoid technology for enhanced biological research. [PDF]

Front Bioeng Biotechnol
García-Aznar JM, McEvoy E, Verbruggen SW, Van Liedekerke P.   +3 more
europepmc   +1 more source

Fabrication, characterization and in vitro release of paclitaxel (Taxol®) loaded poly (lactic-co-glycolic acid) microspheres prepared by spray drying technique with lipid/cholesterol emulsifiers

, 2001
Mu Li, Sheng Feng
openalex   +2 more sources

Collaborative program AVRDC/CIRAD : Set up of techniques for: Onion breeding and galrlic dissemination [PDF]

, 2005
Chang, C.H., Cherng, S.J., Engle, L.M., Féréol, Léonidas, Gniffke, P.A., Green, S., Ledesma, D.R.   +6 more
core  

Smart Nanogels as Enzyme‐Driven Nanomotors for Navigating Viscous Physiological Barriers

Advanced Functional Materials, EarlyView.
Two families of urease‐powered nanomotors (NMs), with and without a p‐(2‐hydroxyethyl methacrylate) (p‐HEMA) shell, have been successfully prepared. Both types exhibit effective motion in highly viscous synovial fluid media at low urea concentrations (25 mM).
David Esporrín‐Ubieto, Noelia Ruiz‐González, Valerio Di Carlo, Daniel Sánchez‐deAlcázar, Florencia Lezcano, Anna Pushkareva Fazullina, Samuel Sánchez   +6 more
wiley   +1 more source

Gold nanoparticle transport across tumour-associated biological barriers: <i>in vitro</i> models, imaging, and quantification.

Nanoscale
Christodoulou C, MacRobert AJ, Loizidou M, Ramesh B, Ricketts K, Thrasivoulou C, Jell G, Patra HK.   +7 more
europepmc   +1 more source

An In Vitro Calibration Model for Vancomycin Quantification in Brain Extracellular Fluid: Toward Improved Dosing in Postoperative Infections. [PDF]

Pharmacol Res Perspect
Žukaitienė S, Žygaitė A, Milkintaitė G, Pancerė J, Balčiūnienė N, Vitkauskienė A, Mačiulaitis R.   +6 more
europepmc   +1 more source