Results 71 to 80 of about 3,163,170 (322)

Electrochemical conversions in a microfluidic chip for xenobiotic metabolism and proteomics [PDF]

open access: yesarXiv, 2018
Albert van den Berg is a full professor on Miniaturized Systems for (Bio)Chemical Analysis at at the University of Twente. In this contribution he describes how microfluidic techniques can be used to mimic xenobiotic metabolism in vitro. Similar devices can also be used to electrochemically cleave proteins for mass spectrometric detection and database ...
arxiv  

Simultaneous Modeling of In Vivo and In Vitro Effects of Nondepolarizing Neuromuscular Blocking Drugs [PDF]

open access: yesarXiv, 2023
Nondepolarizing neuromuscular blocking drugs (NDNBs) are clinically used to produce muscle relaxation during general anesthesia. This paper explores a suitable model structure to simultaneously describe in vivo and in vitro effects of three clinically used NDNBs, cisatracurium, vecuronium, and rocuronium. In particular, it is discussed how to reconcile
arxiv  

Propagation of pistachio applying in vitro culture techniques [PDF]

open access: yesActa Horticulturae, 2017
Peer ...
Marín Velázquez, Juan Antonio   +4 more
openaire   +4 more sources

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

BiodentineTM is cytocompatible with human primary osteoblasts

open access: yesBrazilian Oral Research, 2017
Calcium silicate-based materials have been widely studied due to their resemblance to, and similar applicability of, mineral trioxide aggregate (MTA).
Miriam Zaccaro SCELZA   +5 more
doaj   +1 more source

Probing DNA interactions with proteins using a single-molecule toolbox: inside the cell, in a test tube, and in a computer [PDF]

open access: yesarXiv, 2015
DNA-interacting proteins have roles multiple processes, many operating as molecular machines which undergo dynamic metastable transitions to bring about their biological function. To fully understand this molecular heterogeneity, DNA and the proteins that bind to it must ideally be interrogated at a single molecule level in their native in vivo ...
arxiv  

Micro- and Macrorheological Properties of Isotropically Cross-linked Actin Networks [PDF]

open access: yes, 2007
Cells make use of semi-flexible biopolymers such as actin or intermediate filaments to control their local viscoelastic response by dynamically adjusting the concentration and type of cross-linker molecules. The microstructure of the resulting networks mainly determines their mechanical properties. It remains an important challenge to relate structural
arxiv   +1 more source

TRPM4 contributes to cell death in prostate cancer tumor spheroids, and to extravasation and metastasis in a zebrafish xenograft model system

open access: yesMolecular Oncology, EarlyView.
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen   +6 more
wiley   +1 more source

Performance of progressive and constant tapered instruments rotary systems at canal preparation

open access: yesRGO: Revista Gaúcha de Odontologia, 2018
Objective: The aim of this study was to compare the performance of two nickel-titanium rotary systems regarding the preparation time, final shape of canal, incidence of aberration, transportation, and fracture of instrument.
Bruna GENARI   +5 more
doaj   +1 more source

In vitro immunological techniques in fascioliasis

open access: yes, 1975
Experiments were conducted to examine ways of monitoring immunological responses in sheep to infection with Fasciola hepatica. The enzyme- linked immunosorbent assay (ELISA), the radioimmunoassay, and the agar gel precipitin technique were evaluated using the same somatic fluke antigen, for sensitivity and accuracy in the serodiagnosis of fascioliasis ...
openaire   +2 more sources

Home - About - Disclaimer - Privacy