Results 81 to 90 of about 3,163,170 (322)

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

Molecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti, Shingo Inagaki, Tuyen Thuy Bich Ho, Akihiro Seki, Keiko Yoshida, Kosuke Satomura, Yoshio Sakai, Shuichi Kaneko, Taro Yamashita   +8 more
wiley   +1 more source

In vitro rumen feed degradability assessed with DaisyII and batch culture: effect of sample size

Italian Journal of Animal Science, 2010
In vitro degradability with DaisyII (D) equipment is commonly performed with 0.5g of feed sample into each filter bag. Literature reported that a reduction of the ratio of sample size to bag surface could facilitate the release of soluble or fine ...
Stefano Schiavon, Lucia Bailoni, Franco Tagliapietra, Mirko Cattani   +3 more
doaj   +1 more source

Clinical significance of stratifying prostate cancer patients through specific circulating genes

Molecular Oncology, EarlyView.
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian, Edouard Jarry, Arynne Santos, Quentin Vesval, Lucie Hamel, Rafael Sanchez‐Salas, Alexis Rompré‐Brodeur, Wassim Kassouf, Raghu Rajan, Fadi Brimo, Marie Duclos, Armen Aprikian, Simone Chevalier   +12 more
wiley   +1 more source

Influenza A-associated severe pneumonia in hospitalized patients: Risk factors and NAI treatments

International Journal of Infectious Diseases, 2020
Objective: The risk factors and the impact of NAI treatments in patients with severe influenza A-associated pneumonia remain unclear. Methods: A multicenter, retrospective, observational study was conducted in Zhejiang, China during a severe influenza ...
Qianda Zou, Shufa Zheng, Xiaochen Wang, Sijia Liu, Jiaqi Bao, Fei Yu, Wei Wu, Xianjun Wang, Bo Shen, Tieli Zhou, Zhigang Zhao, Yiping Wang, Ruchang Chen, Wei Wang, Jianbo Ma, Yongcheng Li, Xiaoyan Wu, Weifeng Shen, Fuyi Xie, Dhanasekaran Vijaykrishna, Yu Chen   +20 more
doaj  

High-speed in vitro intensity diffraction tomography [PDF]

, 2019
We demonstrate a label-free, scan-free {\it intensity} diffraction tomography technique utilizing annular illumination (aIDT) to rapidly characterize large-volume 3D refractive index distributions in vitro. By optimally matching the illumination geometry to the microscope pupil, our technique reduces the data requirement by 60$\times$ to achieve high ...
arxiv   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Effets de champignons MA sur la croissance et le développement de plants de ricin élevés sous contrainte saline en conditions semi-contrôlées

Revue des Énergies Renouvelables, 2016
Contexte- La salinité constitue un des principaux facteurs abiotiques limitant la croissance et le rendement des espèces végétales. Les champignons Mycorhizes Arbusculaires, ‘MA’ peuvent réduire les pertes de rendement des végétaux soumis au stress salin.
B. Diallo, S.A.N. Samba, D. Sane
doaj  

A feasible in vitro method to evaluate bacterial infiltration in three implant-abutment connection systems

Journal of Oral Research
Introduction: Microorganism infiltration through the im-plant-abutment interface causes oral health problems such as periimplantitis, leading to implant loss. Materials and Methods: A feasible new method to quantify the Streptococcus mutans (S.
Alexandre Cavalcante de Queiroz, Ivana Barbosa Suffredini, José Dimas de Oliveira, Jefferson de Souza Silva, Eduardo Fernandes Bondan   +4 more
doaj   +1 more source

Effect of Probiotics on Dental Caries and Periodontal Pathogens: An In Vitro Study

Journal of Orofacial Sciences, 2019
Introduction: Probiotics are microorganisms that are administered in live forms and can improve health and well being of human beings. Literature about their antimicrobial activity against oral pathogens is limited.
Subhajit Routh, Mithun Pai, Gururaghavendran Rajesh, Ramya Shenoy, Swapna Sarit   +4 more
doaj   +1 more source