Results 1 to 10 of about 1,182,881 (192)
Synthesis, In Vitro Testing, and Biodistribution of Surfactant-Free Radioactive Nanoparticles for Cancer Treatment [PDF]
Nanomaterials, 2022 New forms of cancer treatment, which are effective, have simple manufacturing processes, and easily transportable, are of the utmost necessity. In this work, a methodology for the synthesis of radioactive Gold-198 nanoparticles without the use of ...
Carla Daruich de Souza +10 more
doaj +2 more sources
Deconvoluting gene and environment interactions to develop an “epigenetic score meter” of disease
EMBO Molecular Medicine, 2023 Human health is determined both by genetics (G) and environment (E). This is clearly illustrated in groups of individuals who are exposed to the same environmental factor showing differential responses.
Alessio Butera +6 more
doaj +1 more source
Life, 2023 Alzheimer’s disease (AD) is a progressive neurodegenerative disease and is the most common type of dementia. Although a considerably large amount of money has been invested in drug development for AD, no disease modifying treatment has been detected so ...
Kyriaki Savva +10 more
doaj +1 more source
Clinical and Translational Medicine, 2021 Background Tumor mutational burden (TMB) is a promising biomarker for stratifying patient subpopulation who would benefit from immune checkpoint blockade (ICB) therapies.
Wenxin Zhang +23 more
doaj +1 more source
Vaccines, 2023 There is increasing interest to replace animal-based potency assays used routinely to test vaccines, since they are highly variable, are costly, and present ethical concerns. The development of relevant in vitro assays is part of the solution.
Jason Szeto +17 more
doaj +1 more source
Recent Progress in Drug Release Testing Methods of Biopolymeric Particulate System
Pharmaceutics, 2021 Biopolymeric microparticles have been widely used for long-term release formulations of short half-life chemicals or synthetic peptides. Characterization of the drug release from microparticles is important to ensure product quality and desired ...
Yejin Kim +3 more
doaj +1 more source
Testing of pandemic ventilators under early and agile development
Frontiers in Medical Technology, 2022 Aiming to address clinical requirements subsequent to SARS-CoV-2-related pulmonary disease, multiple research groups and industry groups carried out intensive studies to develop pandemic ventilators (PDVs).
Nikolaos Tachatos +7 more
doaj +1 more source
Isolation, cultivation, and in vitro susceptibility testing of Borrelia burgdorferi sensu lato: A review [PDF]
Archives of Biological Sciences, 2013 Lyme borreliosis is the most common vector-borne disease in the northern hemisphere. The agents of Lyme borreliosis are borrelia, bacteria of the family Spirochaetaceae, which are grouped in Borrelia burgdorferi sensu lato species complex.
Veinović Gorana +2 more
doaj +1 more source
Open Veterinary Journal, 2023 Background: Vaccination is widely used in fish aquaculture for three primary reasons: to prevent bacterial disease spreading, minimize antibiotic use and fight antibiotic resistance.
Antonella Di-Paolo +4 more
doaj +1 more source
Informing Selection of Nanomaterial Concentrations for ToxCast In Vitro Testing based on Occupational Exposure Potential [PDF]
, 2011 Background: Little justification is generally provided for selection of in vitro assay testing concentrations for engineered nanomaterials (ENMs). Selection of concentration levels for hazard evaluation based on real-world exposure scenarios is desirable.
Gangwal, Sumit +6 more
core +1 more source