Preclinical Analysis of JAA-F11, a Specific Anti-Thomsen-Friedenreich Antibody via Immunohistochemistry and In Vivo Imaging. [PDF]
The tumor specificity of JAA-F11, a novel monoclonal antibody specific for the Thomsen-Friedenreich cancer antigen (TF-Ag-alpha linked), has been comprehensively studied by in vitro immunohistochemical (IHC) staining of human tumor and normal tissue ...
Adams, Julia +13 more
core +2 more sources
Analysis of Common Causes of Out-of-Specification Results in the Test for Depressor Substances
According to General Chapter 1145 of Division IV in the Chinese Pharmacopoeia (2020 Edition), the test for depressor substances is a common method for drug testing.
TONG Xiyang +4 more
doaj +1 more source
Clinical and molecular characterization of a cardiac ryanodine receptor founder mutation causing catecholaminergic polymorphic ventricular tachycardia [PDF]
Background Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a difficult-to-diagnose cause of sudden cardiac death (SCD). We identified a family of 1400 individuals with multiple cases of CPVT, including 36 SCDs during youth.
Allegue, Catarina +12 more
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Differential Responses of Human iPSC-Derived Microglia to Stimulation with Diverse Inflammogens
Human microglia are central regulators and actors in brain infections and neuro-inflammatory pathologies. However, access to such cells is limited, and studies systematically mapping the spectrum of their inflammatory states are scarce.
Chiara Wolfbeisz +9 more
doaj +1 more source
Severe bloodstream infection due to KPC-producer e coli in a renal transplant recipient treated with the double-carbapenem regimen and analysis of in vitro synergy testing a case report [PDF]
Transplant recipients are at high risk of infections caused by multidrug resistant microorganisms. Due to the limited thera- peutic options, innovative antimicrobial combinations against carbape- nem-resistant Enterobacteriaceae causing severe infections
CIPOLLA, ALESSIA +11 more
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Failure characteristics of all polyethylene cemented glenoid implants in total shoulder arthroplasty [PDF]
Total shoulder arthroplasty (TSA) still suffers today from mid-term and long-term complications such as glenoid implant loosening, wear, humeral head subluxation/dislocation and implant fracture. Unlike the hip and knee joint replacements, the artificial
Junaid, Sarah, Junaid, Sarah
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New histone deacetylase inhibitors as potential therapeutic tools for advanced prostate carcinoma [PDF]
The anti-epileptic drug valproic acid is also under trial as an anti-cancer agent due to its histone deacetylase (HDAC) inhibitory properties. However, the effects of valproic acid (VPA) are limited and concentrations required for exerting anti ...
Atmaca, Akin +8 more
core +1 more source
Objective Preimplantation genetic testing for monogenic disorders (PGT-M) has been used for over 20 years to detect many serious genetic conditions. However, there is still a lack of reference materials (RMs) to validate the test performance during the ...
Weihua Zhao +11 more
doaj +1 more source
The granulometric characterization of synthetic amorphous silica (SAS) nanomaterials (NMs) still demands harmonized standard operation procedures. SAS is produced as either precipitated, fumed (pyrogenic), gel and colloidal SAS and these qualities differ,
Rodrigo R. Retamal Marín +4 more
doaj +1 more source
The Testing of in Vitro Ketoconazole Susceptibility on the Causative Agent of Glabrous Skin Dermatophytosis in Makassar [PDF]
Glabrous skin dermatophytosis is dermatophytosis that affects hairless skin areas which are devided into tinea corporis, tinea cruris and tinea facialis.
Hatta, T. H. (Triani)
core

