Results 121 to 130 of about 2,670,044 (299)
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
Molecular Oncology, EarlyView.In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza +3 more
wiley +1 more source
Scientific ReportsThe estrus cycle in female rodents has been shown to affect a variety of physiological functions. However, little is known about its presumably thorough effect on auditory processing during the sleep–wake cycle and sleep deprivation.
Attila Tóth +5 more
doaj +1 more source
THE CONVERSION OF 5-METHYLDEOXYCYTIDINE TO THYMIDINE IN VITRO AND IN VIVO
, 1957 Seymour S. Cohen, Hazel D. Barner
openalex +1 more source
Experimental studies on the differentiation of embryonic tissues growing in vivo and in vitro .—II. The development of the isolated early embryonic eye of the fowl when cultivated in vitro [PDF]
, 1926 T. S. P. Strangeways, Honor B. Fell
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Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Multiparameter MRI quantification of microstructural tissue alterations in multiple sclerosis
NeuroImage: Clinical, 2019 Objectives: Conventional MRI is not sensitive to many pathological processes underpinning multiple sclerosis (MS) ongoing in normal appearing brain tissue (NABT).
Emilie Lommers +8 more
doaj
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Molecular Oncology, EarlyView.Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza +5 more
wiley +1 more source
PATHWAYS FROM GLUCONIC ACID TO GLUCOSE IN VIVO
, 1953 Marjorie R. Stetten, Yale J. Topper
openalex +1 more source