Results 151 to 160 of about 3,388,289 (318)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Introduzione

open access: yes, 2009
Introduzione al volume, si discute dell'importanza del Tableau économique e dei tentativi di Sraffa e Mattioli di trovare una copia del suo testo originario, andato perso (ma ritrovato in anni ...
DE VIVO, GIANCARLO
core  

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

A. cantoniensis Inhibits the Proliferation of Murine Leukemia WEHI-3 Cells In Vivo and Promotes Immunoresponses In Vivo

open access: yes, 2010
[[abstract]]Ampelopsis cantoniensis (AC) has been used as a folk medicine for reducing pain in the Taiwanese population. Our previous studies have shown that the crude extract of AC induced apoptosis in human promyelocytic leukemia HL-60 cells.
Tan, TW (Tan, Tzu-Wei); Lin, YT (Lin, Yuh-Tzy); Yang, JS (Yang, Jai-Sing); Lu, CC (Lu, Chi-Cheng); Chiang, JH (Chiang, Jo-Hua); Wu, CL (Wu, Chang-Lin); Lin, JP (Lin, Jing-Pin); Tang, NY (Tang, Nou-Ying); Yeh, CC (Yeh, Chin-Chung); Fan, MJ (Fan, Ming-Jen); Chung, JG (Chung, Jing-Gung)
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Vesuvius and Campi Flegrei volcanic risk in Neapolitan area

open access: yes, 2015
Valutazione del rischio di potenziali eruzioni dei vulcani attivi del Vesuvio e dei Campi ...
DE VIVO, BENEDETTO
core  

Improved Radiofrequency Safety Modelling in MRI Using In Vivo Measurements of Brain Conductivity. [PDF]

open access: yesNMR Biomed
Paillart G   +7 more
europepmc   +1 more source

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