Results 191 to 200 of about 5,806,183 (351)

Data from Pancreatic Cancer–Specific Cell Death Induced <i>In Vivo</i> by Cytoplasmic-Delivered Polyinosine–Polycytidylic Acid

, 2023
Praveen Bhoopathi, Bridget A. Quinn, Qin Gui, Xue‐Ning Shen, Steven R. Grossman, Swadesh K. Das, Devanand Sarkar, Paul B. Fisher, Luni Emdad   +8 more
openalex   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

In vivo CAR-T engineering: insights from the 2025 ASH annual meeting. [PDF]

Exp Hematol Oncol
Asadi G, Rajabinejad M.
europepmc   +1 more source

Decision letter: An automated high-resolution in vivo screen in zebrafish to identify chemical regulators of myelination

, 2018

openalex   +1 more source

Supplementary Figures 1-2 from Reversible Kinetic Analysis of Myc Targets <i>In vivo</i> Provides Novel Insights into Myc-Mediated Tumorigenesis

, 2023
Elizabeth R. Lawlor, Laura Soucek, Lamorna Brown Swigart, Ksenya Shchors, Carl Uli Bialucha, Gérard I. Evan   +5 more
openalex   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Author Correction: In vivo marker of brainstem myelin is associated to quantitative sleep parameters in healthy young men

Scientific Reports
Puneet Talwar, Michele Deantoni, Maxime Van Egroo, Vincenzo Muto, Daphne Chylinski, Ekaterina Koshmanova, Mathieu Jaspar, Christelle Meyer, Christian Degueldre, Christian Berthomier, André Luxen, Eric Salmon, Fabienne Collette, D.-J. Dijk, Christina Schmidt, Christophe Phillips, Pierre Maquet, Siya Sherif, Gilles Vandewalle   +18 more
doaj   +1 more source

Translational pathology in drug discovery

Frontiers in Pharmacology
Snježana Čužić, Maja Antolić, Anja Ognjenović, Vuk Milutinović, Sonja Vidović Iviš, Ines Glojnarić, Martina Bosnar, Lidija Požgaj, Ema Prenc, Vesna Eraković Haber   +9 more
doaj   +1 more source

From <i>Ex Vivo</i> to <i>In Vivo</i>: Advances in Lentiviral Vector Engineering for CAR-T Therapy. [PDF]

Immune Netw
Baek Y, Seo YR, Kim S, Jung S, Kim CH, Lee YH.   +5 more
europepmc   +1 more source

Data from CD1d-Restricted T Cells License B Cells to Generate Long-Lasting Cytotoxic Antitumor Immunity <i>In vivo</i>

, 2023
Yeonseok Chung, Byung‐Seok Kim, Yeon‐Jeong Kim, Hyun‐Jeong Ko, Sung‐Youl Ko, Dong‐Hyeon Kim, Chang‐Yuil Kang   +6 more
openalex   +1 more source