Results 221 to 230 of about 5,806,183 (351)

Genetic and pharmacologic inhibition of calcineurin reduces biofilm formation by the pathogenic fungus Trichosporon asahii in an in vivo silkworm infection model. [PDF]

PLoS One
Matsumoto Y, Shimizu Y, Nakayama M, Takizawa M, Kurakado S, Sugita T.   +5 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Extensive particle size reduction of wheat bran increases the broiler's caecal fermentative capacity, but not bran fermentability ex vivo. [PDF]

Poult Sci
Vanderghinste P, Bautil A, Simmonds SJ, Apajalahti J, Bedford MR, González-Ortiz G, Courtin CM.   +6 more
europepmc   +1 more source

<i>Pik3ca</i>^H1047R increases cell proliferation and enrichment of luminal progenitors <i>in vivo</i>.

, 2012
Anjali Tikoo, Vincent Roh, G. Montgomery Karen, Ivan Ivetac, Waring Paul, Rebecca Pelzer, Hare Lauren, Shackleton Mark, Humbert Patrick, A. Phillips Wayne   +9 more
openalex   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Commissioning of a near real-time in vivo film dosimetry system. [PDF]

J Appl Clin Med Phys
Yang Y, Lim SB, Das I, Park J, Tang G, Wang D, Hyun M, He X, Chan M.   +8 more
europepmc   +1 more source

Development of a synthetic biology approach to targeted directed evolution of proteins in vivo

, 2013
Thomas Adie
openalex   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

In Vivo CAR-T Therapies-A New Era of Programmable Immunity. [PDF]

Int J Mol Sci
Pierini S, Qureshi R, Pustylnikov S, Bartosh Z, Akimova T.   +4 more
europepmc   +1 more source

Fsn0503 inhibits angiogenesis <i>in vivo</i>; CD34 Immunohistochemical analysis of Fsn0503 treated tumors.

, 2015
Claire Ward, Diana Kuehn, E. Burden Roberta, A. Gormley Julie, Jacques Thomas, Mihaela Gazdoiu, Small Donna, Bicknell Roy, A. Johnston James, Scott Christopher J., A. Olwill Shane   +10 more
openalex   +2 more sources