Results 131 to 140 of about 15,949 (247)

The Development and Evaluation of Novel Reagents for Pre-Targeted Radioimmunotherapy [PDF]

, 2004
PhDIn a pretargeting radioimmunotherapy system, monoclonal antibodies (MAbs) derivatised with a high affinity streptavidin receptor are used in a localisation step.
Hainsworth, James Edward Scott
core  

Selective de-implementation of routine in vivo dosimetry. [PDF]

J Appl Clin Med Phys, 2023
Mao SPH, Han-Oh S, Moore J, Huang E, McNutt TR, Souranis AN, Briner V, Halthore A, Alcorn SR, Meyer JJ, Viswanathan AN, Wright JL.   +11 more
europepmc   +1 more source

Systematic review of physical and dosimetric criteria for managing CIEDs in radiotherapy: A medical physicist's perspective

Journal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.
Abstract Aim Current radiotherapy (RT) guidelines for Cardiac Implantable Electronic Devices (CIEDs) are largely based on clinical management strategies and retrospective reports. This systematic review adopts a medical physics perspective to provide a critical, quantitative analysis of the technical evidence required for developing robust safety ...
Tiziana Malatesta, Agnese Barbareschi, Rita Alaimo, Emilio Mezzenga, Maria Grazia Brambilla, Anna Delana, Stefano Andreoli, Rita Consorti, Stefano Ren Kaiser, Marco Mapelli, Eugenia Moretti, Maria Mormile, Giulia Rambaldi Guidasci, Mara Severgnini, Lidia Strigari, Maria Daniela Falco   +15 more
wiley   +1 more source

Impact of MRI slice thickness and fiducial marker orientation on geometric accuracy in multi‐echo GRE imaging for prostate radiotherapy planning

Journal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.
Abstract Background Precise target definition in prostate radiotherapy requires accurate computed tomography (CT)‐magnetic resonance imaging (MRI) image registration using gold fiducial markers (GFMs). While multi‐echo gradient recalled echo (ME GRE) sequences facilitate GFM identification, the quantitative impact of acquisition parameters on physical ...
Aika Hayashi, Yasukata Takahashi, Naoko Sanuki, Yasufumi Yamashita, Yoshitaka Suzuki, Kanae Matsuura, Hiroe Muto   +6 more
wiley   +1 more source

Affinity‐Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

Advanced Healthcare Materials, Volume 15, Issue 29, 7 August 2026.
Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He, Nicholas L. Fletcher, Gayathri R. Ediriweera, Yifei Zhu, James Humphries, Christopher B. Howard, Jiazheng Wang, Craig A. Bell, Kristian Kempe, Kristofer J. Thurecht   +9 more
wiley   +1 more source

Catching errors with in vivo EPID dosimetry. [PDF]

, 2010
The potential for detrimental incidents and the ever increasing complexity of patient treatments emphasize the need for accurate dosimetric verification in radiotherapy.
Tielenburg, R, Mijnheer, B, Wendling, M, Stroom, J C, Sonke, J J, van Herk, M, Mans, A, Van Herk, Marcel; id_orcid, Vijlbrief, R, McDermott, L N   +9 more
core  

A scintillation dosimeter with real-time positional tracking information for in vivo dosimetry error detection in HDR brachytherapy. [PDF]

J Appl Clin Med Phys, 2023
Tho D, Lavallée MC, Beaulieu L.
europepmc   +1 more source

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

Advanced Science, Volume 13, Issue 46, 17 August 2026.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma, Rui Guo, Dongfeng Niu, Yufei Song, Zhenyao Zhang, Xiangxi Meng, Lili Mao, Haifeng Huang, Hua Zhu, Zhi Yang, Teli Liu   +10 more
wiley   +1 more source

Towards quantitative in vivo dosimetry using x-ray acoustic computed tomography. [PDF]

Med Phys, 2023
Sun L, Gonzalez G, Pandey PK, Wang S, Kim K, Limoli C, Chen Y, Xiang L.   +7 more
europepmc   +1 more source

All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species

Advanced Science, Volume 13, Issue 45, 13 August 2026.
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao, Abulaihaiti Tuergong, Hanshu Yang, Shuang Xue, An Yan, Mingzhen Wang, Weilong Song, Wenzhe Si, Ruixue Wang   +8 more
wiley   +1 more source