Results 111 to 120 of about 1,733,123 (312)
, 2021 BACKGROUND: Postinflammatory hyperpigmentation (PIH) is a common, acquired pigmentary disorder of the skin associated with significant quality-of-life impairment, especially in individuals with skin of colour.
Zhou, Li +17 more
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Development of an In-Vivo Model to Record Motor Neuron Activity in the Awake, Behaving Rat
, 2017 The purpose of this study was to develop an in-vivo model to record motor neuron (MN) activity in the awake, behaving rat. This model is necessary for subsequent studies in which specific ion channels, thought to regulate MN activity, will be blocked ...
Kaur, Pareena
core
Neurotoxicity evaluation of meloxicam in the alternative in vivo model, Caenorhabditis elegans
, 2020 Inflammatory processes cause changes in the permeability of the blood brain barrier. Non-steroidal anti-inflammatory drugs (NSAID) are most commonly used to treat these inflammatory processes, including meloxicam, and they can reach the central nervous ...
Veiverberg, Andriele +7 more
core +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
, 2001 The diagnostic performance of a newly described variable was assessed in an in vivo model of disc degeneration using a split-pair experimental ...
Hansson, Tommy H., +5 more
core
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Sthread: In-Vivo Model Checking of Multithreaded Programs
, 2020 International audienceThis work strives to make formal verification of POSIX multithreaded programs easily accessible to general programmers. Sthread operates directly on multithreaded C/C++ programs, without the need for an intermediate formal model ...
Cooperman, Gene, Quinson, Martin
core +2 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
A porcine in-vivo model of acute pulmonary embolism [PDF]
, 2017 Acute pulmonary embolism (PE) is the third most common cardiovascular cause of death after acute myocardial infarction and stroke. Patients are, however, often under-treated due to the risks associated with systemic thrombolysis and surgical embolectomy.
Andersen, Asger +11 more
core +1 more source