Results 91 to 100 of about 1,733,123 (312)

Histomorphometric Evaluation of Subchronic and Chronic Effects of Novel Experimental Calcium Aluminate- and Calcium Silicate-Based Dental Cement Materials on Rat Liver, Kidney, Brain, and Spleen Tissues

Journal of Functional Biomaterials
Although biocompatible calcium silicate cements (CSCs) and calcium aluminate cements (CACs) may induce local and systemic adverse effects. This study aimed to evaluate the subchronic and chronic effects of experimental CAC and CSC mixtures on rat liver ...
Veljko Ilić, Sanja Milutinović-Smiljanić, Vladimir Biočanin, Jovana Kuzmanović Pfićer, Tatjana Tasić, Vesna Danilović, Nina Japundžić-Žigon, Smiljana Paraš, Vukoman Jokanović, Dejan Ćetković, Đorđe Antonijević   +10 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Caenorhabditis elegans as an alternative in vivo model to determine oral uptake, nanotoxicity, and efficacy of melatonin-loaded lipid-core nanocapsules on paraquat damage

, 2015
Mariele Feiffer Charão,1,2 Caroline Souto,2 Natália Brucker,1,2 Anelise Barth,1,2 Denise S Jornada,1,3 Daiandra Fagundez,4 Daiana Silva Ávila,4 Vera L Eifler-Lima,1,5 Silvia S Guterres,1,3 Adriana R Pohlmann,1,6 Solange Cristina ...
Souto C, Ávila DS, Fagundez D, Pohlmann AR, Charão MF, Barth A, Guterres SS, Garcia SC, Jornada DS, Eifler-Lima VL, Brucker N   +10 more
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Models for Studying Angiogenesis in Vivo

The International Journal of Biological Markers, 1999
In vivo and in vitro techniques are available for reseach on the functions of endothelial cells during angiogenesis. In this review we describe and evaluate the methodology and specific features of some of the most frequently used in vivo assays.
RIBATTI, Domenico, VACCA, Angelo
openaire   +2 more sources

Zebrafish: An in vivo model for the study of neurological diseases

, 2008
J D Best, Wendy K AldertonSummit (Cambridge) Ltd., Beach Drive, Cambridge, UKAbstract: As the population ages, there is a growing need for effective therapies for the treatment of neurological diseases.
Wendy K Alderton, J D Best
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

A novel in vivo model of puncture-induced iris neovascularization.

, 2017
To assess iris neovascularization by uveal puncture of the mouse eye and determine the role of angiogenic factors during iris neovascularization.Uveal punctures were performed on BalbC mouse eyes to induce iris angiogenesis.
Locri, F,, Aronsson, M, Monica Aronsson, Beaujean, O, Ophélie Beaujean, Filippo Locri, Helder André, Kvanta, A,, Andre, H,, Anders Kvanta   +9 more
core   +1 more source

Annexin A5 scintigraphy of forearm as a novel in vivo model of skeletal muscle preconditioning in humans. [PDF]

, 2005
Contains fulltext : 48561.pdf (Publisher’s version ) (Open Access)BACKGROUND: Nonlethal ischemia and reperfusion reduce ischemia-reperfusion-induced cell death, a phenomenon called ischemic preconditioning. In animal models, this potent
Ramakers, B.P.C., Boerman, O.C., Steinmetz, N., Smits, P., Rongen, G.A.P.J.M., Oyen, W.J.G., Riksen, N.P.   +6 more
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source